Nucleus and Mitochondria Targeting Theranostic Plasmonic Surface-Enhanced Raman Spectroscopy Nanoprobes as a Means for Revealing Molecular Stress Response Differences in Hyperthermia Cell Death between Cancerous and Normal Cells.

Qi, Guohua; Zhang, Ying; Xu, Shuping; Li, Chuanping; Wang, Dandan; Li, Haijuan; Jin, Yongdong

Qi, Guohua; Zhang, Ying; Xu, Shuping; Li, Chuanping; Wang, Dandan; Li, Haijuan; Jin, Yongdong.

Affiliation

Qi G; State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry , Chinese Academy of Sciences , Changchun 130022 , Jilin , People's Republic of China.
Zhang Y; University of Chinese Academy of Sciences , Beijing 100049 , People's Republic of China.
Xu S; State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry , Chinese Academy of Sciences , Changchun 130022 , Jilin , People's Republic of China.
Li C; University of Science and Technology of China , Hefei 230026 , People's Republic of China.
Wang D; State Key Laboratory of Supramolecular Structure and Materials , Jilin University , 2699 Qianjin Avenue , Changchun 130012 , People's Republic of China.
Li H; State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry , Chinese Academy of Sciences , Changchun 130022 , Jilin , People's Republic of China.
Jin Y; University of Chinese Academy of Sciences , Beijing 100049 , People's Republic of China.

Anal Chem ; 90(22): 13356-13364, 2018 11 20.

Article in En | MEDLINE | ID: mdl-30234969

Subject(s)

Cell Nucleus/metabolism; Mitochondria/metabolism; Nanoshells/chemistry; Quantum Dots/chemistry; Spectrum Analysis, Raman/methods; Theranostic Nanomedicine/methods; Apoptosis/drug effects; Carbon/chemistry; Carbon/radiation effects; Cell-Penetrating Peptides/chemistry; Cell-Penetrating Peptides/metabolism; DNA/metabolism; DNA Fragmentation/drug effects; Gold/chemistry; Gold/radiation effects; HeLa Cells; Humans; Hyperthermia, Induced/methods; Infrared Rays; Nanoshells/radiation effects; Neoplasms/metabolism; Nuclear Localization Signals/chemistry; Nuclear Localization Signals/metabolism; Quantum Dots/radiation effects; Silver/chemistry; Silver/radiation effects

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Full text: 1 Database: MEDLINE Main subject: Spectrum Analysis, Raman / Cell Nucleus / Quantum Dots / Nanoshells / Theranostic Nanomedicine / Mitochondria Language: En Journal: Anal Chem Year: 2018 Type: Article

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