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Development of a BiTE®-mediated CD8+ cytotoxic T-lymphocyte activity assay to assess immunomodulatory potential of drug candidates in Cynomolgus macaque.
Frank, Brendon; Wei, Yu-Ling; Kim, Kyung-Hoon; Guerrero, Abraham; Lebrec, Hervé; Balazs, Mercedesz; Wang, Xiaoting.
Affiliation
  • Frank B; a Comparative Biology and Safety Sciences , Amgen Inc. , South San Francisco , CA , USA.
  • Wei YL; a Comparative Biology and Safety Sciences , Amgen Inc. , South San Francisco , CA , USA.
  • Kim KH; a Comparative Biology and Safety Sciences , Amgen Inc. , South San Francisco , CA , USA.
  • Guerrero A; a Comparative Biology and Safety Sciences , Amgen Inc. , South San Francisco , CA , USA.
  • Lebrec H; b Diagnostics and Biomarkers , Seattle Genetics , Seattle , WA , USA.
  • Balazs M; a Comparative Biology and Safety Sciences , Amgen Inc. , South San Francisco , CA , USA.
  • Wang X; a Comparative Biology and Safety Sciences , Amgen Inc. , South San Francisco , CA , USA.
J Immunotoxicol ; 15(1): 119-125, 2018 12.
Article in En | MEDLINE | ID: mdl-30241454
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Full text: 1 Database: MEDLINE Main subject: Immunoassay / CD8-Positive T-Lymphocytes / Macaca fascicularis Language: En Journal: J Immunotoxicol Year: 2018 Type: Article Affiliation country: United States
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Full text: 1 Database: MEDLINE Main subject: Immunoassay / CD8-Positive T-Lymphocytes / Macaca fascicularis Language: En Journal: J Immunotoxicol Year: 2018 Type: Article Affiliation country: United States