Endothelium-dependent vasodilatory effect of <i>Smilax china</i> Linn. water extract via PI3K/Akt signaling.

Tettey, Clement Okraku; Yang, In-Jun; Shin, Heung-Mook

Endothelium-dependent vasodilatory effect of Smilax china Linn. water extract via PI3K/Akt signaling.

Tettey, Clement Okraku; Yang, In-Jun; Shin, Heung-Mook.

Affiliation

Tettey CO; Department of Biomedical Sciences, University of Health and Allied Sciences, Ho, Ghana.
Yang IJ; Department of Physiology College of Korean Medicine, Dongguk University, Gyeongju, South Korea.
Shin HM; Department of Physiology College of Korean Medicine, Dongguk University, Gyeongju, South Korea.

Arch Physiol Biochem ; 126(3): 209-213, 2020 Jul.

Article in En | MEDLINE | ID: mdl-30269606

Subject(s)

Endothelium, Vascular/metabolism; Plant Extracts/pharmacology; Signal Transduction/drug effects; Smilax/chemistry; Vasodilation/drug effects; Vasodilator Agents/pharmacology; Animals; Aorta/drug effects; Cell Survival; Human Umbilical Vein Endothelial Cells; Humans; Male; NG-Nitroarginine Methyl Ester/pharmacology; Nitric Oxide; Nitrites/pharmacology; Phenylephrine/pharmacology; Phosphatidylinositol 3-Kinases/metabolism; Phosphorylation; Proto-Oncogene Proteins c-akt/metabolism; Rats; Rats, Sprague-Dawley; Wortmannin/pharmacology

Key words

L-NAME; Vasodilation; aorta; endothelium; phosphorylation

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Full text: 1 Database: MEDLINE Main subject: Vasodilation / Vasodilator Agents / Endothelium, Vascular / Plant Extracts / Signal Transduction / Smilax Language: En Journal: Arch Physiol Biochem Year: 2020 Type: Article Affiliation country: Ghana

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