Ginsenoside Rg3 and Rh2 protect trimethyltin-induced neurotoxicity via prevention on neuronal apoptosis and neuroinflammation.

Hou, Jingang; Xue, Jianjie; Wang, Zi; Li, Wei

Hou, Jingang; Xue, Jianjie; Wang, Zi; Li, Wei.

Affiliation

Hou J; College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun, China.
Xue J; Intelligent Synthetic Biology Center, Daejeon, Republic of Korea.
Wang Z; Qingdao Municipal Center for Disease Control and Prevention, Qingdao, China.
Li W; Qingdao Institute of Preventive Medicine, Qingdao, China.

Phytother Res ; 32(12): 2531-2540, 2018 Dec.

Article in En | MEDLINE | ID: mdl-30277284

Subject(s)

Encephalitis/prevention & control; Ginsenosides/pharmacology; Neurons/drug effects; Neuroprotective Agents/pharmacology; Animals; Antioxidants/pharmacology; Apoptosis/drug effects; Cell Death/drug effects; Cells, Cultured; Embryo, Mammalian; Encephalitis/chemically induced; Encephalitis/pathology; Neurons/physiology; Neuroprotection/drug effects; Neurotoxicity Syndromes/prevention & control; Oxidative Stress/drug effects; Rats; Rats, Sprague-Dawley; Trimethyltin Compounds

Key words

Rg3 and Rh2; TMT; neuroinflammation; oligodendrocyte progenitor cells (O-2A); oxidative stress

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Full text: 1 Database: MEDLINE Main subject: Neuroprotective Agents / Ginsenosides / Encephalitis / Neurons Language: En Journal: Phytother Res Year: 2018 Type: Article Affiliation country: China

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