Paeoniflorin attenuates oxidized low-density lipoprotein-induced apoptosis and adhesion molecule expression by autophagy enhancement in human umbilical vein endothelial cells.

Wang, Yi; Che, Jianbo; Zhao, Hui; Tang, Jianyu; Shi, Gongning

Wang, Yi; Che, Jianbo; Zhao, Hui; Tang, Jianyu; Shi, Gongning.

Affiliation

Wang Y; Department of Cardiothoracic Surgery, Huaihe Hospital of Henan University, Kaifeng, China.
Che J; Department of Cardiothoracic Surgery, Huaihe Hospital of Henan University, Kaifeng, China.
Zhao H; Department of Cardiothoracic Surgery, Huaihe Hospital of Henan University, Kaifeng, China.
Tang J; Department of Cardiothoracic Surgery, Huaihe Hospital of Henan University, Kaifeng, China.
Shi G; Department of Cardiothoracic Surgery, Huaihe Hospital of Henan University, Kaifeng, China.

J Cell Biochem ; 120(6): 9291-9299, 2019 06.

Article in En | MEDLINE | ID: mdl-30548681

Subject(s)

Blood Vessels/drug effects; Glucosides/pharmacology; Lipoproteins, LDL/genetics; Monoterpenes/pharmacology; Sirtuin 1/genetics; Antioxidants/pharmacology; Apoptosis/drug effects; Autophagy/drug effects; Blood Vessels/injuries; Carbazoles/pharmacology; Cell Adhesion Molecules/genetics; Cell Survival/drug effects; Gene Expression Regulation/drug effects; Human Umbilical Vein Endothelial Cells; Humans; Lipoproteins, LDL/antagonists & inhibitors; Oxidative Stress/drug effects; Signal Transduction/drug effects

Key words

autophagy; human umbilical vein endothelial cells (HUVECs); oxidized low-density lipoprotein (ox-LDL); paeoniflorin (Pae); sirtuin1 (SIRT1)

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Full text: 1 Database: MEDLINE Main subject: Blood Vessels / Monoterpenes / Sirtuin 1 / Glucosides / Lipoproteins, LDL Language: En Journal: J Cell Biochem Year: 2019 Type: Article Affiliation country: China

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