New bisbibenzyl and phenanthrene derivatives from Dendrobium scabrilingue and their α-glucosidase inhibitory activity.
Nat Prod Res
; 34(12): 1694-1701, 2020 Jun.
Article
in En
| MEDLINE
| ID: mdl-30580616
ABSTRACT
Phytochemical investigation of the whole plant of Dendrobium scabrilingue resulted in the isolation of two new compounds namely dendroscabrols A (1) and B (2), along with eight known compounds (3-10). The structures of these compounds were determined by NMR and HR-ESI-MS experiments. All of the isolates were evaluated for their α-glucosidase inhibitory effect. Dendroscabrol B (2) and RF-3192C (10) showed the most potent α-glucosidase inhibitory activity. Dendroscabrol A (1), gigantol (5), coelonin (7) and lusianthridin (9) also exhibited strong activity as compared with the positive control acarbose.
Key words
Full text:
1
Database:
MEDLINE
Main subject:
Phenanthrenes
/
Bibenzyls
/
Dendrobium
/
Glycoside Hydrolase Inhibitors
Language:
En
Journal:
Nat Prod Res
Year:
2020
Type:
Article
Affiliation country:
Thailand