Your browser doesn't support javascript.
loading
New bisbibenzyl and phenanthrene derivatives from Dendrobium scabrilingue and their α-glucosidase inhibitory activity.
Sarakulwattana, Chalermporn; Mekboonsonglarp, Wanwimon; Likhitwitayawuid, Kittisak; Rojsitthisak, Pornchai; Sritularak, Boonchoo.
Affiliation
  • Sarakulwattana C; Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand.
  • Mekboonsonglarp W; Scientific and Technological Research Equipment Centre Chulalongkorn University, Bangkok, Thailand.
  • Likhitwitayawuid K; Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand.
  • Rojsitthisak P; Natural Products for Ageing and Chronic Diseases Research Unit, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand.
  • Sritularak B; Department of Food and Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand.
Nat Prod Res ; 34(12): 1694-1701, 2020 Jun.
Article in En | MEDLINE | ID: mdl-30580616
ABSTRACT
Phytochemical investigation of the whole plant of Dendrobium scabrilingue resulted in the isolation of two new compounds namely dendroscabrols A (1) and B (2), along with eight known compounds (3-10). The structures of these compounds were determined by NMR and HR-ESI-MS experiments. All of the isolates were evaluated for their α-glucosidase inhibitory effect. Dendroscabrol B (2) and RF-3192C (10) showed the most potent α-glucosidase inhibitory activity. Dendroscabrol A (1), gigantol (5), coelonin (7) and lusianthridin (9) also exhibited strong activity as compared with the positive control acarbose.
Subject(s)
Key words
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Database: MEDLINE Main subject: Phenanthrenes / Bibenzyls / Dendrobium / Glycoside Hydrolase Inhibitors Language: En Journal: Nat Prod Res Year: 2020 Type: Article Affiliation country: Thailand
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Database: MEDLINE Main subject: Phenanthrenes / Bibenzyls / Dendrobium / Glycoside Hydrolase Inhibitors Language: En Journal: Nat Prod Res Year: 2020 Type: Article Affiliation country: Thailand