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Drug repositioning screening identifies etravirine as a potential therapeutic for friedreich's ataxia.
Alfedi, Giulia; Luffarelli, Riccardo; Condò, Ivano; Pedini, Giorgia; Mannucci, Liliana; Massaro, Damiano S; Benini, Monica; Toschi, Nicola; Alaimo, Giorgia; Panarello, Luca; Pacini, Laura; Fortuni, Silvia; Serio, Dario; Malisan, Florence; Testi, Roberto; Rufini, Alessandra.
Affiliation
  • Alfedi G; Laboratory of Signal Transduction, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", Rome, Italy.
  • Luffarelli R; Laboratory of Signal Transduction, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", Rome, Italy.
  • Condò I; Laboratory of Signal Transduction, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", Rome, Italy.
  • Pedini G; Laboratory of Molecular Neurobiology, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", Rome, Italy.
  • Mannucci L; Laboratory of Molecular Neurobiology, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", Rome, Italy.
  • Massaro DS; Laboratory of Signal Transduction, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", Rome, Italy.
  • Benini M; Laboratory of Signal Transduction, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", Rome, Italy.
  • Toschi N; Fratagene Therapeutics Srl, Rome, Italy.
  • Alaimo G; Medical Physics Section, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", Rome, Italy.
  • Panarello L; Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging and Harvard Medical School, Boston, Massachusetts, USA.
  • Pacini L; Laboratory of Signal Transduction, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", Rome, Italy.
  • Fortuni S; Fratagene Therapeutics Srl, Rome, Italy.
  • Serio D; Laboratory of Signal Transduction, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", Rome, Italy.
  • Malisan F; Laboratory of Molecular Neurobiology, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", Rome, Italy.
  • Testi R; Laboratory of Signal Transduction, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", Rome, Italy.
  • Rufini A; Laboratory of Signal Transduction, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", Rome, Italy.
Mov Disord ; 34(3): 323-334, 2019 03.
Article in En | MEDLINE | ID: mdl-30624801
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Full text: 1 Database: MEDLINE Main subject: Pyridazines / Friedreich Ataxia / Iron-Binding Proteins Type of study: Diagnostic_studies / Screening_studies Language: En Journal: Mov Disord Year: 2019 Type: Article Affiliation country: Italy
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Full text: 1 Database: MEDLINE Main subject: Pyridazines / Friedreich Ataxia / Iron-Binding Proteins Type of study: Diagnostic_studies / Screening_studies Language: En Journal: Mov Disord Year: 2019 Type: Article Affiliation country: Italy