Nanoscale bubble ultrasound contrast agents-mediated suicide gene therapy system, Nanoscale bubble-LV5-YCD-TK/GCV/5-FC, effectively inhibits bladder cancer cell growth.

Fu, Y-R; Chen, F; Luo, Y; Yi, Y-F

Fu, Y-R; Chen, F; Luo, Y; Yi, Y-F.

Affiliation

Fu YR; Department of Urology, The Peoples Hospital of Nanchuan Chongqing, Chongqing, China. yiyongfdr@outlook.com.

Eur Rev Med Pharmacol Sci ; 23(1): 75-86, 2019 Jan.

Article in En | MEDLINE | ID: mdl-30657549

Subject(s)

Drug Delivery Systems/methods; Genes, Transgenic, Suicide/genetics; Genetic Therapy/methods; Microbubbles/therapeutic use; Urinary Bladder Neoplasms/therapy; Cell Cycle Checkpoints/drug effects; Cell Cycle Checkpoints/genetics; Cell Line, Tumor; Cell Proliferation/drug effects; Cell Proliferation/genetics; Cell Survival/drug effects; Cell Survival/genetics; Chemoradiotherapy/methods; Contrast Media/therapeutic use; Cytosine Deaminase/genetics; Fungal Proteins/genetics; Ganciclovir/administration & dosage; Genetic Vectors/administration & dosage; Genetic Vectors/genetics; Humans; Nanoparticles/therapeutic use; Precision Medicine/methods; Recombinant Proteins/genetics; Thymidine Kinase/genetics; Transfection; Urinary Bladder/pathology; Urinary Bladder Neoplasms/genetics; Urinary Bladder Neoplasms/pathology; Viral Proteins/genetics

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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Plantas_medicinales Main subject: Urinary Bladder Neoplasms / Genetic Therapy / Drug Delivery Systems / Microbubbles / Genes, Transgenic, Suicide Language: En Journal: Eur Rev Med Pharmacol Sci Year: 2019 Type: Article Affiliation country: China

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