Calcium Channel Blockers Possibly Delay the Elimination of Plasma Methotrexate in Patients Receiving High-Dose Methotrexate Therapy.

Inose, Ryo; Takahashi, Katsuyuki; Nanno, Satoru; Hino, Masayuki; Nagayama, Katsuya

Inose, Ryo; Takahashi, Katsuyuki; Nanno, Satoru; Hino, Masayuki; Nagayama, Katsuya.

Affiliation

Inose R; a Department of Pharmacy , Osaka City University Hospital , Osaka , Japan.
Takahashi K; a Department of Pharmacy , Osaka City University Hospital , Osaka , Japan.
Nanno S; b Department of Hematology , Graduate School of Medicine, Osaka City University , Osaka , Japan.
Hino M; b Department of Hematology , Graduate School of Medicine, Osaka City University , Osaka , Japan.
Nagayama K; a Department of Pharmacy , Osaka City University Hospital , Osaka , Japan.

J Chemother ; 31(1): 30-34, 2019 Feb.

Article in En | MEDLINE | ID: mdl-30773130

Subject(s)

Antimetabolites, Antineoplastic/pharmacokinetics; Calcium Channel Blockers/administration & dosage; Methotrexate/pharmacokinetics; Adult; Aged; Antimetabolites, Antineoplastic/administration & dosage; Antimetabolites, Antineoplastic/blood; Drug Interactions; Female; Humans; Lymphoma/drug therapy; Male; Methotrexate/administration & dosage; Methotrexate/blood; Middle Aged; Retrospective Studies

Key words

Amlodipine; Calcium channel blocker; Delayed elimination; Interactive drug; Lymphoma; Methotrexate

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Full text: 1 Database: MEDLINE Main subject: Calcium Channel Blockers / Methotrexate / Antimetabolites, Antineoplastic Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Language: En Journal: J Chemother Year: 2019 Type: Article Affiliation country: Japan

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