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BW18, a C-21 steroidal glycoside, exerts an excellent anti-leukemia activity through inducing S phase cell cycle arrest and apoptosis via MAPK pathway in K562 cells.
Yang, Jue; Chen, Li; Yan, Ying; Qiu, Jianfei; Chen, Juan; Song, Jingrui; Rao, Qing; Ben-David, Yaacov; Li, Yanmei; Hao, Xiaojiang.
Affiliation
  • Yang J; The State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academic of Sciences, Guiyang 550014, China.
  • Chen L; Guiyang University of Chinese Medicine, Guiyang 550025, China.
  • Yan Y; The State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academic of Sciences, Guiyang 550014, China.
  • Qiu J; The State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academic of Sciences, Guiyang 550014, China.
  • Chen J; The State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academic of Sciences, Guiyang 550014, China.
  • Song J; The State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academic of Sciences, Guiyang 550014, China.
  • Rao Q; The State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academic of Sciences, Guiyang 550014, China.
  • Ben-David Y; The State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academic of Sciences, Guiyang 550014, China.
  • Li Y; The State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academic of Sciences, Guiyang 550014, China. Electronic address: liyanmei518@hotmail.com
  • Hao X; The State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China; The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academic of Sciences, Guiyang 550014, China. Electronic address: haoxj2013@126.com.
Biomed Pharmacother ; 112: 108603, 2019 Apr.
Article in En | MEDLINE | ID: mdl-30784914
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Full text: 1 Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Main subject: Phytosterols / S Phase / Apoptosis / MAP Kinase Signaling System / Glycosides / Antineoplastic Agents Type of study: Prognostic_studies Language: En Journal: Biomed Pharmacother Year: 2019 Type: Article Affiliation country: China
Fulltext
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Full text: 1 Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Main subject: Phytosterols / S Phase / Apoptosis / MAP Kinase Signaling System / Glycosides / Antineoplastic Agents Type of study: Prognostic_studies Language: En Journal: Biomed Pharmacother Year: 2019 Type: Article Affiliation country: China