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Platelet-Rich Plasma as a Treatment for Androgenetic Alopecia.
Gupta, Aditya K; Cole, John; Deutsch, David P; Everts, Peter A; Niedbalski, Robert P; Panchaprateep, Ratchathorn; Rinaldi, Fabio; Rose, Paul T; Sinclair, Rodney; Vogel, James E; Welter, Ryan J; Zufelt, Michael D; Puig, Carlos J.
Affiliation
  • Gupta AK; International Society of Hair Restoration Surgery (ISHRS), Ad Hoc Committee on PRP.
  • Cole J; Division of Dermatology, Department of Medicine, University of Toronto School of Medicine, Toronto, Ontario, Canada.
  • Deutsch DP; Cole Hair Transplant Group, Alpharetta, Georgia.
  • Everts PA; International Society of Hair Restoration Surgery (ISHRS), Ad Hoc Committee on PRP.
  • Niedbalski RP; Bosley Medical, Beverly Hills, California.
  • Panchaprateep R; EmCyte Corporation, Fort Myers, Florida.
  • Rinaldi F; International Society of Hair Restoration Surgery (ISHRS), Ad Hoc Committee on PRP.
  • Rose PT; Northwest Hair Restoration, Tacoma, Washington.
  • Sinclair R; International Society of Hair Restoration Surgery (ISHRS), Ad Hoc Committee on PRP.
  • Vogel JE; Division of Dermatology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
  • Welter RJ; International Society of Hair Restoration Surgery (ISHRS), Ad Hoc Committee on PRP.
  • Zufelt MD; International Hair Research Foundation, Italy.
  • Puig CJ; International Society of Hair Restoration Surgery (ISHRS), Ad Hoc Committee on PRP.
Dermatol Surg ; 45(10): 1262-1273, 2019 10.
Article in En | MEDLINE | ID: mdl-30882509
BACKGROUND: Platelet-rich plasma (PRP) treatment may encourage hair growth by promoting cellular maturation, differentiation, and proliferation. OBJECTIVE: The objective of this study was to evaluate the effectiveness of PRP as a treatment for androgenetic alopecia (AGA). MATERIALS AND METHODS: A literature search combined with meta-analysis was used to calculate the overall standardized mean difference (SMD) in hair density in patients treated with PRP injections in comparison with baseline and placebo treatment. Chi squared analysis and Fisher exact test were used to investigate variation in protocols. RESULTS: The overall SMD in hair density was 0.58 (95% confidence interval [CI]: 0.35-0.80) and 0.51 (95% CI: 0.23-0.80, p < .0004) in favor of PRP treatment when compared with baseline and placebo treatment, respectively. CONCLUSION: Platelet-rich plasma is beneficial in the treatment of AGA. It is recommended that 3 monthly sessions of PRP (once monthly ×3 treatments) be used followed by a 3- to 6-month maintenance period.
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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_biologicas / Hemoterapia Main subject: Blood Transfusion, Autologous / Alopecia / Platelet-Rich Plasma Type of study: Clinical_trials / Guideline / Systematic_reviews Language: En Journal: Dermatol Surg Year: 2019 Type: Article
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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_biologicas / Hemoterapia Main subject: Blood Transfusion, Autologous / Alopecia / Platelet-Rich Plasma Type of study: Clinical_trials / Guideline / Systematic_reviews Language: En Journal: Dermatol Surg Year: 2019 Type: Article