Genetic characteristics and antibiotic resistance of Haemophilus influenzae isolates from pediatric patients with acute otitis media after introduction of 13-valent pneumococcal conjugate vaccine in Japan.

Ubukata, Kimiko; Morozumi, Miyuki; Sakuma, Megumi; Adachi, Yoko; Mokuno, Eriko; Tajima, Takeshi; Iwata, Satoshi

Ubukata, Kimiko; Morozumi, Miyuki; Sakuma, Megumi; Adachi, Yoko; Mokuno, Eriko; Tajima, Takeshi; Iwata, Satoshi.

Affiliation

Ubukata K; Department of Infectious Diseases, Keio University, School of Medicine, Tokyo, Japan. Electronic address: ubukatak@keio.jp.
Morozumi M; Department of Infectious Diseases, Keio University, School of Medicine, Tokyo, Japan.
Sakuma M; Department of Infectious Diseases, Keio University, School of Medicine, Tokyo, Japan.
Adachi Y; Department of Infectious Diseases, Keio University, School of Medicine, Tokyo, Japan.
Mokuno E; Department of Otorhinolaryngology, Hakujikai Memorial Hospital, Tokyo, Japan.
Tajima T; Department of Pediatrics, Hakujikai Memorial Hospital, Tokyo, Japan.
Iwata S; Department of Infectious Diseases, National Cancer Center Hospital, Tokyo, Japan.

J Infect Chemother ; 25(9): 720-726, 2019 Sep.

Article in En | MEDLINE | ID: mdl-30987951

Subject(s)

Drug Resistance, Multiple, Bacterial/genetics; Haemophilus Infections/drug therapy; Haemophilus Infections/microbiology; Haemophilus influenzae/drug effects; Haemophilus influenzae/genetics; Otitis Media/drug therapy; Otitis Media/microbiology; Pneumococcal Vaccines/therapeutic use; Acute Disease; Ampicillin/therapeutic use; Anti-Bacterial Agents/therapeutic use; Carbapenems/therapeutic use; Cephalosporins/therapeutic use; Child, Preschool; Fluoroquinolones/therapeutic use; Haemophilus influenzae/isolation & purification; Humans; Infant; Japan; Microbial Sensitivity Tests; Multilocus Sequence Typing; Naphthyridines/therapeutic use; Quinolones/therapeutic use; Streptococcus pneumoniae/drug effects; Streptococcus pneumoniae/isolation & purification; Vaccines, Conjugate/therapeutic use; beta-Lactam Resistance/genetics

Key words

Acute otitis media; Genotypic resistance; Haemophilus influenzae; Multilocus sequence typing; Quinolone resistance; gBLNAR

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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Plantas_medicinales Main subject: Otitis Media / Haemophilus influenzae / Pneumococcal Vaccines / Drug Resistance, Multiple, Bacterial / Haemophilus Infections Type of study: Prognostic_studies Country/Region as subject: Asia Language: En Journal: J Infect Chemother Year: 2019 Type: Article

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