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IGF-1 reverses the osteogenic inhibitory effect of dexamethasone on BMP9-induced osteogenic differentiation in mouse embryonic fibroblasts via PI3K/AKT/COX-2 pathway.
Jiang, Hai-Tao; Ran, Cheng-Cheng; Liao, Yun-Peng; Zhu, Jia-Hui; Wang, Han; Deng, Rui; Nie, Mao; He, Bai-Cheng; Deng, Zhong-Liang.
Affiliation
  • Jiang HT; Department of Orthopaedics, The Second Affiliated Hospital of Chongqing Medical University, 76 Linjiang Road, Yuzhong District, Chongqing 400010, PR China; Chongqing Key Laboratory of Biochemistry and Molecular Pharmacology, Chongqing Medical University, No. 1 Yixueyuan Road, Yuzhong District, Chong
  • Ran CC; Department of Orthopaedics, The Second Affiliated Hospital of Chongqing Medical University, 76 Linjiang Road, Yuzhong District, Chongqing 400010, PR China; Chongqing Key Laboratory of Biochemistry and Molecular Pharmacology, Chongqing Medical University, No. 1 Yixueyuan Road, Yuzhong District, Chong
  • Liao YP; Chongqing Key Laboratory of Biochemistry and Molecular Pharmacology, Chongqing Medical University, No. 1 Yixueyuan Road, Yuzhong District, Chongqing 400010, PR China; Department of Pharmacology, School of Pharmacy, Chongqing Medical University, No. 1 Yixueyuan Road, Yuzhong District, Chongqing 40001
  • Zhu JH; Chongqing Key Laboratory of Biochemistry and Molecular Pharmacology, Chongqing Medical University, No. 1 Yixueyuan Road, Yuzhong District, Chongqing 400010, PR China; Department of Pharmacology, School of Pharmacy, Chongqing Medical University, No. 1 Yixueyuan Road, Yuzhong District, Chongqing 40001
  • Wang H; Chongqing Key Laboratory of Biochemistry and Molecular Pharmacology, Chongqing Medical University, No. 1 Yixueyuan Road, Yuzhong District, Chongqing 400010, PR China; Department of Pharmacology, School of Pharmacy, Chongqing Medical University, No. 1 Yixueyuan Road, Yuzhong District, Chongqing 40001
  • Deng R; Department of Orthopaedics, The Second Affiliated Hospital of Chongqing Medical University, 76 Linjiang Road, Yuzhong District, Chongqing 400010, PR China.
  • Nie M; Department of Orthopaedics, The Second Affiliated Hospital of Chongqing Medical University, 76 Linjiang Road, Yuzhong District, Chongqing 400010, PR China.
  • He BC; Chongqing Key Laboratory of Biochemistry and Molecular Pharmacology, Chongqing Medical University, No. 1 Yixueyuan Road, Yuzhong District, Chongqing 400010, PR China; Department of Pharmacology, School of Pharmacy, Chongqing Medical University, No. 1 Yixueyuan Road, Yuzhong District, Chongqing 40001
  • Deng ZL; Department of Orthopaedics, The Second Affiliated Hospital of Chongqing Medical University, 76 Linjiang Road, Yuzhong District, Chongqing 400010, PR China. Electronic address: zhongliang.deng@yahoo.com.
J Steroid Biochem Mol Biol ; 191: 105363, 2019 07.
Article in En | MEDLINE | ID: mdl-31018166
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Full text: 1 Database: MEDLINE Main subject: Osteogenesis / Insulin-Like Growth Factor I / Dexamethasone / Growth Differentiation Factor 2 / Fibroblasts / Glucocorticoids Language: En Journal: J Steroid Biochem Mol Biol Year: 2019 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Osteogenesis / Insulin-Like Growth Factor I / Dexamethasone / Growth Differentiation Factor 2 / Fibroblasts / Glucocorticoids Language: En Journal: J Steroid Biochem Mol Biol Year: 2019 Type: Article