Wheat alkylresorcinols protect human retinal pigment epithelial cells against H<sub>2</sub>O<sub>2</sub>-induced oxidative damage through Akt-dependent Nrf2/HO-1 signaling.

Wang, Ziyuan; Hao, Yiming; Wang, Yu; Liu, Jie; Yuan, Xiaoping; Sun, Baoguo; Wang, Jing

Wheat alkylresorcinols protect human retinal pigment epithelial cells against H₂O₂-induced oxidative damage through Akt-dependent Nrf2/HO-1 signaling.

Wang, Ziyuan; Hao, Yiming; Wang, Yu; Liu, Jie; Yuan, Xiaoping; Sun, Baoguo; Wang, Jing.

Affiliation

Wang Z; China-Canada Joint Lab of Food Nutrition and Health (Beijing), Beijing Technology & Business University (BTBU), Beijing 100048, China. wangjing@th.btbu.edu.cn.

Food Funct ; 10(5): 2797-2804, 2019 May 22.

Article in En | MEDLINE | ID: mdl-31049492

Subject(s)

Heme Oxygenase-1/metabolism; NF-E2-Related Factor 2/metabolism; Oxidative Stress/drug effects; Plant Extracts/pharmacology; Protective Agents/pharmacology; Proto-Oncogene Proteins c-akt/metabolism; Resorcinols/pharmacology; Triticum/chemistry; Apoptosis/drug effects; Cell Line; Epithelial Cells/cytology; Epithelial Cells/drug effects; Epithelial Cells/metabolism; Heme Oxygenase-1/genetics; Humans; Hydrogen Peroxide/toxicity; NF-E2-Related Factor 2/genetics; Proto-Oncogene Proteins c-akt/genetics; Reactive Oxygen Species/metabolism; Retinal Pigment Epithelium/cytology; Retinal Pigment Epithelium/drug effects; Retinal Pigment Epithelium/metabolism

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Full text: 1 Database: MEDLINE Main subject: Resorcinols / Triticum / Plant Extracts / Oxidative Stress / Protective Agents / Heme Oxygenase-1 / Proto-Oncogene Proteins c-akt / NF-E2-Related Factor 2 Language: En Journal: Food Funct Year: 2019 Type: Article Affiliation country: China

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