Preadministration of high-dose alpha-tocopherol improved memory impairment and mitochondrial dysfunction induced by proteasome inhibition in rat hippocampus.

Nesari, Ali; Mansouri, Mohammad Taghi; Khodayar, Mohammad Javad; Rezaei, Mohsen

Nesari, Ali; Mansouri, Mohammad Taghi; Khodayar, Mohammad Javad; Rezaei, Mohsen.

Affiliation

Nesari A; Department of Toxicology, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Mansouri MT; Department of Pharmacology, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Khodayar MJ; Department of Anesthesiology, Irving Medical Center, Columbia University, New York, NY, USA.
Rezaei M; Department of Toxicology, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Nutr Neurosci ; 24(2): 119-129, 2021 Feb.

Article in En | MEDLINE | ID: mdl-31084475

Subject(s)

Hippocampus/drug effects; Memory, Long-Term/drug effects; Mitochondria/drug effects; Neuroprotective Agents/administration & dosage; alpha-Tocopherol/administration & dosage; Animals; Hippocampus/metabolism; Male; Mitochondria/metabolism; Oxidative Stress/drug effects; Proteasome Endopeptidase Complex; Proteasome Inhibitors/administration & dosage; Rats, Wistar

Key words

Alpha-tocopherol; Memory; Mitochondria; Proteasome; Rat; Reactive Oxygen Species

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Full text: 1 Database: MEDLINE Main subject: Neuroprotective Agents / Alpha-Tocopherol / Memory, Long-Term / Hippocampus / Mitochondria Language: En Journal: Nutr Neurosci Year: 2021 Type: Article Affiliation country: Iran

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