Isolation of Myricitrin and 3,5-di-O-Methyl Gossypetin from <i>Syzygium samarangense</i> and Evaluation of their Involvement in Protecting Keratinocytes against Oxidative Stress via Activation of the Nrf-2 Pathway.

Sobeh, Mansour; Petruk, Ganna; Osman, Samir; El Raey, Mohamed A; Imbimbo, Paola; Monti, Daria Maria; Wink, Michael

Isolation of Myricitrin and 3,5-di-O-Methyl Gossypetin from Syzygium samarangense and Evaluation of their Involvement in Protecting Keratinocytes against Oxidative Stress via Activation of the Nrf-2 Pathway.

Sobeh, Mansour; Petruk, Ganna; Osman, Samir; El Raey, Mohamed A; Imbimbo, Paola; Monti, Daria Maria; Wink, Michael.

Affiliation

Sobeh M; Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, 69120 Heidelberg, Germany. sobeh@uni-heidelberg.de.
Petruk G; AgroBioSciences Research Division, Mohammed VI Polytechnic University, Lot 660â»Hay Moulay Rachid, 43150 Ben-Guerir, Morocco. sobeh@uni-heidelberg.de.
Osman S; Department of Chemical Sciences, University of Naples Federico II, Complesso Universitario Monte Sant'Angelo, via Cinthia 4, 80126 Naples, Italy. ganna.petruk@unina.it.
El Raey MA; Department of Pharmacognosy, Faculty of Pharmacy, October 6 University, Giza 12585, Egypt. samirothman1965@yahoo.co.uk.
Imbimbo P; Department of Phytochemistry and Plant Systematics, National Research Center, Dokki, Cairo 12622, Egypt. elraiy@gmail.com.
Monti DM; Department of Chemical Sciences, University of Naples Federico II, Complesso Universitario Monte Sant'Angelo, via Cinthia 4, 80126 Naples, Italy. Paola.Imbimbo@unina.it.
Wink M; Department of Chemical Sciences, University of Naples Federico II, Complesso Universitario Monte Sant'Angelo, via Cinthia 4, 80126 Naples, Italy. mdmonti@unina.it.

Molecules ; 24(9)2019 May 13.

Article in En | MEDLINE | ID: mdl-31086086

Subject(s)

Flavonoids/chemistry; Flavonoids/pharmacology; Keratinocytes/drug effects; Keratinocytes/metabolism; Syzygium/chemistry; Antioxidants/metabolism; Cell Line; Flavonoids/metabolism; Humans; NF-E2-Related Factor 2/metabolism; Oxidation-Reduction/drug effects; Oxidative Stress/drug effects; Reactive Oxygen Species/metabolism

Key words

3,5-di-O-methyl gossypetin; Syzygium samarangense; antioxidants; eukaryotic cells; myricitrin; sodium arsenite

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Full text: 1 Database: MEDLINE Main subject: Flavonoids / Keratinocytes / Syzygium Language: En Journal: Molecules Year: 2019 Type: Article Affiliation country: Germany

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