Micronized, Heat-Treated <i>Lactobacillus plantarum</i> LM1004 Alleviates Cyclophosphamide-Induced Immune Suppression.

Jung, Il Seon; Jeon, Min Gyu; Oh, Da Som; Jung, Ye Jin; Kim, Hyun-Su; Bae, Donghyuck; Kim, Yujin; Lee, Gyeong-Eun; Choi, Chulyung; Hwang, Yong Pil

Micronized, Heat-Treated Lactobacillus plantarum LM1004 Alleviates Cyclophosphamide-Induced Immune Suppression.

Jung, Il Seon; Jeon, Min Gyu; Oh, Da Som; Jung, Ye Jin; Kim, Hyun-Su; Bae, Donghyuck; Kim, Yujin; Lee, Gyeong-Eun; Choi, Chulyung; Hwang, Yong Pil.

Affiliation

Jung IS; Centre for Research and Development, LactoMason Co., Ltd., Jinju, Korea.
Jeon MG; Centre for Research and Development, LactoMason Co., Ltd., Jinju, Korea.
Oh DS; Centre for Research and Development, LactoMason Co., Ltd., Jinju, Korea.
Jung YJ; Centre for Research and Development, LactoMason Co., Ltd., Jinju, Korea.
Kim HS; Centre for Research and Development, LactoMason Co., Ltd., Jinju, Korea.
Bae D; Jeonnam Bioindustry Foundation, Jeonnam Institute of Natural Resources Research, Jangheung-gun, Korea.
Kim Y; Jeonnam Bioindustry Foundation, Jeonnam Institute of Natural Resources Research, Jangheung-gun, Korea.
Lee GE; Jeonnam Bioindustry Foundation, Jeonnam Institute of Natural Resources Research, Jangheung-gun, Korea.
Choi C; Jeonnam Bioindustry Foundation, Jeonnam Institute of Natural Resources Research, Jangheung-gun, Korea.
Hwang YP; Department of Pharmaceutical Engineering, International University of Korea, Jinju, Korea.

J Med Food ; 22(9): 896-906, 2019 Sep.

Article in En | MEDLINE | ID: mdl-31216204

Subject(s)

Antineoplastic Agents, Alkylating/adverse effects; Cyclophosphamide/adverse effects; Immunologic Factors/administration & dosage; Immunomodulation/drug effects; Lactobacillus plantarum/chemistry; Probiotics/administration & dosage; Animals; Antineoplastic Agents, Alkylating/administration & dosage; Cyclophosphamide/administration & dosage; Female; Hot Temperature; Immunosuppression Therapy; Interferon-gamma/genetics; Interferon-gamma/immunology; Interleukin-12/genetics; Interleukin-12/immunology; Interleukin-2/genetics; Interleukin-2/immunology; Killer Cells, Natural/drug effects; Killer Cells, Natural/immunology; Macrophages/drug effects; Macrophages/immunology; Mice; Mice, Inbred BALB C; Phagocytosis/drug effects; Tumor Necrosis Factor-alpha/genetics; Tumor Necrosis Factor-alpha/immunology

Key words

NK cell activity; cyclophosphamide; cytokine; heat-treated Lactobacillus plantarum LM1004; immune enhancement; macrophage phagocytosis

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Full text: 1 Database: MEDLINE Main subject: Antineoplastic Agents, Alkylating / Probiotics / Cyclophosphamide / Lactobacillus plantarum / Immunomodulation / Immunologic Factors Type of study: Prognostic_studies Language: En Journal: J Med Food Year: 2019 Type: Article

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