Attenuation of diabetic nephropathy by dietary fenugreek (Trigonella foenum-graecum) seeds and onion (Allium cepa) via suppression of glucose transporters and renin-angiotensin system.

Pradeep, Seetur R; Barman, Susmita; Srinivasan, Krishnapura

Pradeep, Seetur R; Barman, Susmita; Srinivasan, Krishnapura.

Affiliation

Pradeep SR; Department of Biochemistry, Central Food Technological Research Institute, Mysore, India.
Barman S; Department of Biochemistry, Central Food Technological Research Institute, Mysore, India.
Srinivasan K; Department of Biochemistry, Central Food Technological Research Institute, Mysore, India. Electronic address: Ksri.cftri@gmail.com.

Nutrition ; 67-68: 110543, 2019.

Article in En | MEDLINE | ID: mdl-31408826

Subject(s)

Diabetes Mellitus, Experimental/drug therapy; Diabetic Nephropathies/drug therapy; Onions; Phytotherapy/methods; Plant Extracts/therapeutic use; Animals; Carbohydrate Metabolism/drug effects; Diabetes Mellitus, Experimental/metabolism; Diabetes Mellitus, Experimental/pathology; Diabetic Nephropathies/metabolism; Diabetic Nephropathies/pathology; Glucose Transport Proteins, Facilitative/antagonists & inhibitors; Hypoglycemic Agents/therapeutic use; Kidney/drug effects; Kidney/metabolism; Kidney/pathology; Male; Membrane Fluidity/drug effects; Nitric Oxide/metabolism; Nitric Oxide/urine; Onions/chemistry; Polymers/metabolism; Proteinuria/drug therapy; Proteinuria/urine; Rats; Rats, Wistar; Renin-Angiotensin System/drug effects; Trigonella

Key words

Diabetic nephropathy; Fenugreek seeds; Glucose transporters; Leaching of renal enzymes; Podocyte damage; Reninangiotensin system

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Full text: 1 Database: MEDLINE Complementary Medicines: Homeopatia Therapeutic Methods and Therapies TCIM: Terapias_biologicas / Plantas_medicinales Main subject: Plant Extracts / Onions / Diabetes Mellitus, Experimental / Diabetic Nephropathies / Phytotherapy Language: En Journal: Nutrition Year: 2019 Type: Article Affiliation country: India

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