Anti-inflammatory flavonoids from root bark of Broussonetia papyrifera in LPS-stimulated RAW264.7 cells.

Ryu, Hyung Won; Park, Mi Hyeon; Kwon, Ok-Kyoung; Kim, Doo-Young; Hwang, Jung-Yeon; Jo, Yang Hee; Ahn, Kyung-Seop; Hwang, Bang Yeon; Oh, Sei-Ryang

Ryu, Hyung Won; Park, Mi Hyeon; Kwon, Ok-Kyoung; Kim, Doo-Young; Hwang, Jung-Yeon; Jo, Yang Hee; Ahn, Kyung-Seop; Hwang, Bang Yeon; Oh, Sei-Ryang.

Affiliation

Ryu HW; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheong-ju si, Chungcheongbuk-do 28116, Republic of Korea.
Park MH; College of Pharmacy, Chungbuk National University, Cheongju 28644, Republic of Korea.
Kwon OK; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheong-ju si, Chungcheongbuk-do 28116, Republic of Korea.
Kim DY; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheong-ju si, Chungcheongbuk-do 28116, Republic of Korea.
Hwang JY; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheong-ju si, Chungcheongbuk-do 28116, Republic of Korea.
Jo YH; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheong-ju si, Chungcheongbuk-do 28116, Republic of Korea.
Ahn KS; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheong-ju si, Chungcheongbuk-do 28116, Republic of Korea.
Hwang BY; College of Pharmacy, Chungbuk National University, Cheongju 28644, Republic of Korea. Electronic address: byhwang@chungbuk.ac.kr.
Oh SR; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheong-ju si, Chungcheongbuk-do 28116, Republic of Korea. Electronic address: seiryang@kribb.re.kr.

Bioorg Chem ; 92: 103233, 2019 11.

Article in En | MEDLINE | ID: mdl-31518759

Subject(s)

Anti-Inflammatory Agents/pharmacology; Broussonetia/chemistry; Flavonoids/pharmacology; Plant Bark/chemistry; Animals; Anti-Inflammatory Agents/isolation & purification; Cell Survival/drug effects; Cyclooxygenase 2/genetics; Dose-Response Relationship, Drug; Flavonoids/isolation & purification; Gene Expression/drug effects; Interleukin-6/antagonists & inhibitors; Lipopolysaccharides; Medicine, Korean Traditional; Mice; Molecular Structure; Nitric Oxide/antagonists & inhibitors; Nitric Oxide Synthase Type II/genetics; RAW 264.7 Cells; Tumor Necrosis Factor-alpha/antagonists & inhibitors

Key words

Anti-inflammatory; Bioactivity-guided isolation; Broussonetia papyrifera; Dihydroflavonol; Diphenylpropane

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Full text: 1 Database: MEDLINE Main subject: Flavonoids / Plant Bark / Broussonetia / Anti-Inflammatory Agents Type of study: Prognostic_studies Language: En Journal: Bioorg Chem Year: 2019 Type: Article

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