Nuclear control of lung cancer cells migration, invasion and bioenergetics by eukaryotic translation initiation factor 3F.

Esteves, Pauline; Dard, Laetitia; Brillac, Aurélia; Hubert, Christophe; Sarlak, Saharnaz; Rousseau, Benoît; Dumon, Elodie; Izotte, Julien; Bonneu, Marc; Lacombe, Didier; Dupuy, Jean-William; Amoedo, Nivea; Rossignol, Rodrigue

Esteves, Pauline; Dard, Laetitia; Brillac, Aurélia; Hubert, Christophe; Sarlak, Saharnaz; Rousseau, Benoît; Dumon, Elodie; Izotte, Julien; Bonneu, Marc; Lacombe, Didier; Dupuy, Jean-William; Amoedo, Nivea; Rossignol, Rodrigue.

Affiliation

Esteves P; Bordeaux University, 146 rue Léo Saignat, 33000, Bordeaux, France.
Dard L; INSERM U1211, 33000, Bordeaux, France.
Brillac A; Bordeaux University, 146 rue Léo Saignat, 33000, Bordeaux, France.
Hubert C; INSERM U1211, 33000, Bordeaux, France.
Sarlak S; Bordeaux University, 146 rue Léo Saignat, 33000, Bordeaux, France.
Rousseau B; INSERM U1211, 33000, Bordeaux, France.
Dumon E; Bordeaux University, 146 rue Léo Saignat, 33000, Bordeaux, France.
Izotte J; INSERM U1211, 33000, Bordeaux, France.
Bonneu M; Bordeaux University, 146 rue Léo Saignat, 33000, Bordeaux, France.
Lacombe D; INSERM U1211, 33000, Bordeaux, France.
Dupuy JW; Bordeaux University, 146 rue Léo Saignat, 33000, Bordeaux, France.
Amoedo N; Transgenic Animal Facility A2, University of Bordeaux, 33000, Bordeaux, France.
Rossignol R; Bordeaux University, 146 rue Léo Saignat, 33000, Bordeaux, France.

Oncogene ; 39(3): 617-636, 2020 01.

Article in En | MEDLINE | ID: mdl-31527668

Subject(s)

Adenocarcinoma of Lung/genetics; Cell Nucleus/metabolism; Energy Metabolism/genetics; Eukaryotic Initiation Factor-3/metabolism; Gene Expression Regulation, Neoplastic; Lung Neoplasms/genetics; STAT3 Transcription Factor/metabolism; A549 Cells; Adenocarcinoma of Lung/metabolism; Adenocarcinoma of Lung/pathology; Animals; Cell Movement/drug effects; Cell Movement/genetics; Cell Nucleus/genetics; Cell Nucleus/pathology; Datasets as Topic; Energy Metabolism/drug effects; Eukaryotic Initiation Factor-3/genetics; Gene Knockdown Techniques; HeLa Cells; Humans; Hydroxybenzoates/pharmacology; Lung/cytology; Lung/pathology; Lung Neoplasms/metabolism; Lung Neoplasms/mortality; Lung Neoplasms/pathology; Male; Mice; Mutation; Neoplasm Invasiveness/genetics; Nitrofurans/pharmacology; Oxidative Phosphorylation/drug effects; RNA, Small Interfering/metabolism; RNA-Seq; STAT3 Transcription Factor/antagonists & inhibitors; STAT3 Transcription Factor/genetics; Snail Family Transcription Factors/genetics; Survival Analysis; Xenograft Model Antitumor Assays

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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_energeticas / Bioenergetica Main subject: Gene Expression Regulation, Neoplastic / Cell Nucleus / Eukaryotic Initiation Factor-3 / Energy Metabolism / STAT3 Transcription Factor / Adenocarcinoma of Lung / Lung Neoplasms Type of study: Prognostic_studies Language: En Journal: Oncogene Year: 2020 Type: Article Affiliation country: France

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