Preparation of an oil suspension containing ondansetron hydrochloride as a sustained release parenteral formulation.

Nguyen, Thi-Thao-Linh; Duong, Van-An; Maeng, Han-Joo; Chi, Sang-Cheol

Nguyen, Thi-Thao-Linh; Duong, Van-An; Maeng, Han-Joo; Chi, Sang-Cheol.

Affiliation

Nguyen TT; College of Pharmacy, Gachon University, 191 Hambakmoero, Yeonsu-gu, Incheon, 21936, South Korea.
Duong VA; College of Pharmacy, Gachon University, 191 Hambakmoero, Yeonsu-gu, Incheon, 21936, South Korea.
Maeng HJ; College of Pharmacy, Gachon University, 191 Hambakmoero, Yeonsu-gu, Incheon, 21936, South Korea.
Chi SC; College of Pharmacy, Gachon University, 191 Hambakmoero, Yeonsu-gu, Incheon, 21936, South Korea. scchi@gachon.ac.kr.

Drug Deliv Transl Res ; 10(1): 282-295, 2020 02.

Article in En | MEDLINE | ID: mdl-31659599

Subject(s)

Drug Compounding/methods; Methylcellulose/chemistry; Ondansetron/administration & dosage; Plant Oils/chemistry; Animals; Biological Availability; Delayed-Action Preparations; Hydrogen-Ion Concentration; Infusions, Parenteral; Injections, Subcutaneous; Male; Ondansetron/chemistry; Ondansetron/pharmacokinetics; Particle Size; Rats; Solubility; Suspensions; Viscosity

Key words

Microparticles; Oil suspension; Ondansetron hydrochloride; Parenteral formulation; Spray drying; Sustained release

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Plant Oils / Ondansetron / Drug Compounding / Methylcellulose Language: En Journal: Drug Deliv Transl Res Year: 2020 Type: Article Affiliation country: South Korea

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google