Anti-Inflammatory Activities of Isogosferol, a Furanocoumarin Isolated from <i>Citrus junos</i> Seed Shells through Bioactivity-Guided Fractionation.

Song, Hwa Young; Jo, Ara; Shin, Jihun; Lim, Eui Hyeon; Lee, Ye Eun; Jeong, Da Eun; Lee, Mina

Anti-Inflammatory Activities of Isogosferol, a Furanocoumarin Isolated from Citrus junos Seed Shells through Bioactivity-Guided Fractionation.

Song, Hwa Young; Jo, Ara; Shin, Jihun; Lim, Eui Hyeon; Lee, Ye Eun; Jeong, Da Eun; Lee, Mina.

Affiliation

Shin J; College of Pharmacy, Sunchon National University, 255 Jungangno, Suncheon-si 57922, Jeonnam, Korea.
Lim EH; Both authors contributed equally to this work..

Molecules ; 24(22)2019 Nov 12.

Article in En | MEDLINE | ID: mdl-31726781

Subject(s)

Anti-Inflammatory Agents/isolation & purification; Anti-Inflammatory Agents/pharmacology; Citrus/chemistry; Furocoumarins/isolation & purification; Furocoumarins/pharmacology; Plant Extracts/isolation & purification; Plant Extracts/pharmacology; Seeds/chemistry; Animals; Anti-Inflammatory Agents/chemistry; Cell Survival/drug effects; Chemical Fractionation; Cyclooxygenase 2/genetics; Cyclooxygenase 2/metabolism; Cytokines/metabolism; Extracellular Signal-Regulated MAP Kinases/metabolism; Furocoumarins/chemistry; Gene Expression Regulation/drug effects; Mice; Nitric Oxide/metabolism; Nitric Oxide Synthase Type II/genetics; Nitric Oxide Synthase Type II/metabolism; Phytochemicals/chemistry; Phytochemicals/isolation & purification; Phytochemicals/pharmacology; Plant Extracts/chemistry; Plant Oils; RAW 264.7 Cells

Key words

Citrus junos seeds; RAW 264.7 cells; bioactivity-guided fractionation; coumarins; inflammatory mediators

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Full text: 1 Database: MEDLINE Main subject: Furocoumarins / Seeds / Plant Extracts / Citrus / Anti-Inflammatory Agents Language: En Journal: Molecules Year: 2019 Type: Article

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