Hypothalamic Monoaminergic Pathology in a Neurodevelopmental Rat Model Showing Prenatal 5-Bromo-2'-Deoxyuridine Treatment-Induced Hyperactivity and Hyporeproductivity.

Kuwagata, Makiko; Muneoka, Katsumasa; Honda, Kazuho; Miyazaki, Akira

Kuwagata, Makiko; Muneoka, Katsumasa; Honda, Kazuho; Miyazaki, Akira.

Affiliation

Kuwagata M; Department of Anatomy, Showa University School of Medicine, Tokyo, Japan.
Muneoka K; Laboratory of Safety Evaluation, Division of Safety, Hatano Research Institute, Food and Drug Safety Center, Hadano, Japan.
Honda K; Division of Cellular and Molecular Toxicology, Center for Biological Safety and Research, National Institute of Health Science, Kawasaki, Japan.
Miyazaki A; Department of Anatomy, Showa University School of Medicine, Tokyo, Japan, kmuneoka@med.showa-u.ac.jp.

Neuropsychobiology ; 79(2): 161-169, 2020.

Article in En | MEDLINE | ID: mdl-31822012

Subject(s)

Corpus Striatum/metabolism; Dopamine/metabolism; Hypothalamus/metabolism; Neurodevelopmental Disorders/metabolism; Serotonin/metabolism; Sex Characteristics; Animals; Antimetabolites/pharmacology; Bromodeoxyuridine/pharmacology; Disease Models, Animal; Female; Male; Neurodevelopmental Disorders/chemically induced; Pregnancy; Prenatal Exposure Delayed Effects/chemically induced; Prenatal Exposure Delayed Effects/metabolism; Rats; Rats, Sprague-Dawley

Key words

Dopamine; Hyperactivity; Hypothalamus; Serotonin; Sexual activity; Striatum

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Full text: 1 Database: MEDLINE Main subject: Dopamine / Serotonin / Sex Characteristics / Corpus Striatum / Neurodevelopmental Disorders / Hypothalamus Type of study: Prognostic_studies Language: En Journal: Neuropsychobiology Year: 2020 Type: Article Affiliation country: Japan

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