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Clinical evidence-guided network pharmacology analysis reveals a critical contribution of ß1-adrenoreceptor upregulation to bradycardia alleviation by Shenxian-Shengmai.
Gao, Jiaming; Wang, Taiyi; Yao, Xi; Xie, Weiwei; Shi, Xianru; He, Shuang; Zhao, Tao; Wang, Chunhua; Zhu, Yan.
Affiliation
  • Gao J; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China.
  • Wang T; Research and Development Center of TCM, Tianjin International Joint Academy of Biotechnology & Medicine, Tianjin, 300457, China.
  • Yao X; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China.
  • Xie W; Research and Development Center of TCM, Tianjin International Joint Academy of Biotechnology & Medicine, Tianjin, 300457, China.
  • Shi X; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China.
  • He S; Research and Development Center of TCM, Tianjin International Joint Academy of Biotechnology & Medicine, Tianjin, 300457, China.
  • Zhao T; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China.
  • Wang C; Research and Development Center of TCM, Tianjin International Joint Academy of Biotechnology & Medicine, Tianjin, 300457, China.
  • Zhu Y; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China.
BMC Complement Altern Med ; 19(1): 357, 2019 Dec 10.
Article in En | MEDLINE | ID: mdl-31822281
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Full text: 1 Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Main subject: Bradycardia / Drugs, Chinese Herbal / Up-Regulation / Receptors, Adrenergic, beta-1 Type of study: Systematic_reviews Language: En Journal: BMC Complement Altern Med Year: 2019 Type: Article Affiliation country: China
Fulltext
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Full text: 1 Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Main subject: Bradycardia / Drugs, Chinese Herbal / Up-Regulation / Receptors, Adrenergic, beta-1 Type of study: Systematic_reviews Language: En Journal: BMC Complement Altern Med Year: 2019 Type: Article Affiliation country: China