Neuroprotective effects of Bacopa monnieri in Parkinson's disease model.

Singh, Babita; Pandey, Shivani; Rumman, Mohammad; Mahdi, Abbas Ali

Singh, Babita; Pandey, Shivani; Rumman, Mohammad; Mahdi, Abbas Ali.

Affiliation

Singh B; Department of Biochemistry, King George's Medical University (KGMU), Lucknow, UP, 226003, India.
Pandey S; Department of Biochemistry, King George's Medical University (KGMU), Lucknow, UP, 226003, India. drshivaninbc@gmail.com.
Rumman M; Department of Biochemistry, King George's Medical University (KGMU), Lucknow, UP, 226003, India.
Mahdi AA; Era University, Lucknow, UP, India.

Metab Brain Dis ; 35(3): 517-525, 2020 03.

Article in En | MEDLINE | ID: mdl-31834548

Subject(s)

Bacopa; Neuroprotective Agents/therapeutic use; Oxidative Stress/drug effects; Parkinson Disease, Secondary/drug therapy; Plant Extracts/therapeutic use; Animals; Cerebral Cortex/drug effects; Cerebral Cortex/metabolism; Chemokine CCL4/metabolism; Disease Models, Animal; Hippocampus/drug effects; Hippocampus/metabolism; Interleukin-1beta/metabolism; Interleukin-6/metabolism; Male; Neuroprotective Agents/pharmacology; Parkinson Disease, Secondary/chemically induced; Parkinson Disease, Secondary/metabolism; Plant Extracts/pharmacology; Rats; Rats, Wistar; Reactive Oxygen Species/metabolism; Rotenone; Substantia Nigra/drug effects; Substantia Nigra/metabolism; Tumor Necrosis Factor-alpha/metabolism; alpha-Synuclein/metabolism

Key words

Bacopa monnieri; Cytokines; Neurodegeneration; Parkinson's disease; ROS

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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_biologicas / Aromoterapia Main subject: Parkinson Disease, Secondary / Plant Extracts / Oxidative Stress / Neuroprotective Agents / Bacopa Type of study: Prognostic_studies Language: En Journal: Metab Brain Dis Year: 2020 Type: Article Affiliation country: India

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