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Neferine induces autophagy-dependent cell death in apoptosis-resistant cancers via ryanodine receptor and Ca2+-dependent mechanism.
Law, Betty Yuen Kwan; Michelangeli, Francesco; Qu, Yuan Qing; Xu, Su-Wei; Han, Yu; Mok, Simon Wing Fai; Dias, Ivo Ricardo de Seabra Rodrigues; Javed, Masood-Ul-Hassan; Chan, Wai-Kit; Xue, Wei-Wei; Yao, Xiao-Jun; Zeng, Wu; Zhang, Hui; Wang, Jing-Rong; Liu, Liang; Wong, Vincent Kam Wai.
Affiliation
  • Law BYK; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.
  • Michelangeli F; School of Biosciences, University of Birmingham, Edgbaston, Birmingham, UK.
  • Qu YQ; Department of Biological Sciences, University of Chester, Chester, UK.
  • Xu SW; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.
  • Han Y; Department of Basic Medicine of Zhuhai health school, Zhuhai, China.
  • Mok SWF; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.
  • Dias IRSR; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.
  • Javed MU; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.
  • Chan WK; College of Medicine, King Saud Bin Abdulaziz University of Health Sciences, King Abdul Aziz Medical City, Jeddah, 21423, Kingdom of Saudi Arabia.
  • Xue WW; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.
  • Yao XJ; College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, Gansu, 730000, P.R. China.
  • Zeng W; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.
  • Zhang H; College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, Gansu, 730000, P.R. China.
  • Wang JR; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.
  • Liu L; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.
  • Wong VKW; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.
Sci Rep ; 9(1): 20034, 2019 12 27.
Article in En | MEDLINE | ID: mdl-31882989
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Full text: 1 Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Main subject: Calcium / Apoptosis / Ryanodine Receptor Calcium Release Channel / Benzylisoquinolines / Autophagic Cell Death / Neoplasms Type of study: Prognostic_studies Language: En Journal: Sci Rep Year: 2019 Type: Article Affiliation country: China
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Full text: 1 Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Main subject: Calcium / Apoptosis / Ryanodine Receptor Calcium Release Channel / Benzylisoquinolines / Autophagic Cell Death / Neoplasms Type of study: Prognostic_studies Language: En Journal: Sci Rep Year: 2019 Type: Article Affiliation country: China