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A new abietane diterpenoid from Ajuga ovalifolia var. calantha induces human lung epithelial A549 cell apoptosis by inhibiting SHP2.
Liu, De-Ming; Cao, Zhi-Xing; Yan, Hong-Ling; Li, Wen; Yang, Fan; Zhao, Wen-Ji; Diao, Qing-Chun; Tan, Yu-Zhu.
Affiliation
  • Liu DM; State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu, China; Department of Dermatology, Chongqing Traditional Chinese Medicine Hospital, Chongqing, China.
  • Cao ZX; State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
  • Yan HL; State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
  • Li W; State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
  • Yang F; State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
  • Zhao WJ; Sichuan Academy of Grassland Sciences, Chengdu, China.
  • Diao QC; Department of Dermatology, Chongqing Traditional Chinese Medicine Hospital, Chongqing, China. Electronic address: qchdiao@vip.sina.com.
  • Tan YZ; State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China, Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu, China. Electronic address: tanyuzhu@cdutcm.edu.cn.
Fitoterapia ; 141: 104484, 2020 Mar.
Article in En | MEDLINE | ID: mdl-31954180
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Full text: 1 Database: MEDLINE Main subject: Apoptosis / Lamiaceae / Abietanes / Diterpenes / Protein Tyrosine Phosphatase, Non-Receptor Type 11 Language: En Journal: Fitoterapia Year: 2020 Type: Article Affiliation country: China
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Full text: 1 Database: MEDLINE Main subject: Apoptosis / Lamiaceae / Abietanes / Diterpenes / Protein Tyrosine Phosphatase, Non-Receptor Type 11 Language: En Journal: Fitoterapia Year: 2020 Type: Article Affiliation country: China