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Melatonin ameliorates the advanced maternal age-associated meiotic defects in oocytes through the SIRT2-dependent H4K16 deacetylation pathway.
Li, Congyang; He, Xi; Huang, Zhenyue; Han, Longsen; Wu, Xinghan; Li, Ling; Xin, Yongan; Ge, Juan; Sha, Jiahao; Yin, Zhiqiang; Wang, Qiang.
Affiliation
  • Li C; State Key Laboratory of Reproductive Medicine, Suzhou Municipal Hospital, Department of Histology and Embryology, Nanjing Medical University, Nanjing, China.
  • He X; State Key Laboratory of Reproductive Medicine, Suzhou Municipal Hospital, Department of Histology and Embryology, Nanjing Medical University, Nanjing, China.
  • Huang Z; State Key Laboratory of Reproductive Medicine, Suzhou Municipal Hospital, Department of Histology and Embryology, Nanjing Medical University, Nanjing, China.
  • Han L; State Key Laboratory of Reproductive Medicine, Suzhou Municipal Hospital, Department of Histology and Embryology, Nanjing Medical University, Nanjing, China.
  • Wu X; State Key Laboratory of Reproductive Medicine, Suzhou Municipal Hospital, Department of Histology and Embryology, Nanjing Medical University, Nanjing, China.
  • Li L; State Key Laboratory of Reproductive Medicine, Suzhou Municipal Hospital, Department of Histology and Embryology, Nanjing Medical University, Nanjing, China.
  • Xin Y; State Key Laboratory of Reproductive Medicine, Suzhou Municipal Hospital, Department of Histology and Embryology, Nanjing Medical University, Nanjing, China.
  • Ge J; State Key Laboratory of Reproductive Medicine, Suzhou Municipal Hospital, Department of Histology and Embryology, Nanjing Medical University, Nanjing, China.
  • Sha J; State Key Laboratory of Reproductive Medicine, Suzhou Municipal Hospital, Department of Histology and Embryology, Nanjing Medical University, Nanjing, China.
  • Yin Z; Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
  • Wang Q; State Key Laboratory of Reproductive Medicine, Suzhou Municipal Hospital, Department of Histology and Embryology, Nanjing Medical University, Nanjing, China.
Aging (Albany NY) ; 12(2): 1610-1623, 2020 01 24.
Article in En | MEDLINE | ID: mdl-31980591

Full text: 1 Database: MEDLINE Main subject: Oocytes / Aging / Histones / Sirtuin 2 / Meiosis / Melatonin Type of study: Prognostic_studies / Risk_factors_studies Language: En Journal: Aging (Albany NY) Year: 2020 Type: Article Affiliation country: China

Full text: 1 Database: MEDLINE Main subject: Oocytes / Aging / Histones / Sirtuin 2 / Meiosis / Melatonin Type of study: Prognostic_studies / Risk_factors_studies Language: En Journal: Aging (Albany NY) Year: 2020 Type: Article Affiliation country: China