Resveratrol for protection against statin toxicity in C2C12 and H9c2 cells.

Attalah Nee Rezkallah, Chama; Thongkum, Angkana; Zhu, Chao; Chen, Qin M

Attalah Nee Rezkallah, Chama; Thongkum, Angkana; Zhu, Chao; Chen, Qin M.

Affiliation

Attalah Nee Rezkallah C; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona.
Thongkum A; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona.
Zhu C; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona.
Chen QM; Department of Pharmacy Practice and Science, College of Pharmacy, University of Arizona, Tucson, Arizona.

J Biochem Mol Toxicol ; 34(6): e22484, 2020 Jun.

Article in En | MEDLINE | ID: mdl-32196851

Subject(s)

Cell Survival/drug effects; Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects; Myoblasts/drug effects; Protective Agents/pharmacology; Resveratrol/pharmacology; Animals; Atorvastatin/adverse effects; Caspase 3/metabolism; Caspase 7/metabolism; Cell Line; Fluvastatin/adverse effects; Lovastatin/adverse effects; Mice; Myoblasts/metabolism; Pravastatin/adverse effects; Rats; Signal Transduction/drug effects; Simvastatin/adverse effects

Key words

cytotoxicity; lipid-lowering drug; metabolic inhibition; nutritional supplement

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Full text: 1 Database: MEDLINE Main subject: Cell Survival / Hydroxymethylglutaryl-CoA Reductase Inhibitors / Protective Agents / Myoblasts / Resveratrol Language: En Journal: J Biochem Mol Toxicol Year: 2020 Type: Article

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