A combat with the YAP/TAZ-TEAD oncoproteins for cancer therapy.

Pobbati, Ajaybabu V; Hong, Wanjin

Pobbati, Ajaybabu V; Hong, Wanjin.

Affiliation

Pobbati AV; Institute of Molecular and Cell Biology, 61 Biopolis Drive, 138673, Singapore.
Hong W; Institute of Molecular and Cell Biology, 61 Biopolis Drive, 138673, Singapore.

Theranostics ; 10(8): 3622-3635, 2020.

Article in En | MEDLINE | ID: mdl-32206112

Subject(s)

Adaptor Proteins, Signal Transducing/antagonists & inhibitors; DNA-Binding Proteins/antagonists & inhibitors; Neoplasms/therapy; Trans-Activators/antagonists & inhibitors; Transcription Factors/antagonists & inhibitors; Adaptor Proteins, Signal Transducing/metabolism; Adaptor Proteins, Signal Transducing/pharmacology; Antineoplastic Agents/pharmacology; Carcinogenesis/drug effects; Carcinogenesis/metabolism; DNA-Binding Proteins/pharmacology; Drug Design; Hippo Signaling Pathway; Humans; Intracellular Signaling Peptides and Proteins/metabolism; Oncogene Proteins/drug effects; Oncogene Proteins/metabolism; Phosphoproteins/metabolism; Protein Serine-Threonine Kinases/metabolism; Signal Transduction/drug effects; Trans-Activators/pharmacology; Transcription Factors/metabolism; Transcription Factors/pharmacology; Transcriptional Coactivator with PDZ-Binding Motif Proteins; YAP-Signaling Proteins

Key words

Hippo; TAZ; TEAD; YAP; cancer therapy

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Plantas_medicinales Main subject: Transcription Factors / Trans-Activators / Adaptor Proteins, Signal Transducing / DNA-Binding Proteins / Neoplasms Type of study: Prognostic_studies Language: En Journal: Theranostics Year: 2020 Type: Article Affiliation country: Singapore

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google