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GluN2A-selective positive allosteric modulator-nalmefene-flumazenil reverses ketamine-fentanyl-dexmedetomidine-induced anesthesia and analgesia in rats.
Li, Chunzhu; Yan, Jia; Tang, Dewei; Zhu, Jidong; Huang, Chen; Sun, Yu; Hu, Rong; Wang, Hao; Fu, Chaoying; Chen, Yelin; Jiang, Hong.
Affiliation
  • Li C; Department of Anesthesiology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Center for Specialty Strategy Research of Shanghai Jiao Tong University China Hospital Development Institute, Shanghai, 200011, China.
  • Yan J; Department of Anesthesiology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Center for Specialty Strategy Research of Shanghai Jiao Tong University China Hospital Development Institute, Shanghai, 200011, China.
  • Tang D; Center for Molecular Imaging, Shanghai University of Medicine & Health Sciences, Shanghai, China.
  • Zhu J; Department of Nuclear Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 160 Pujian Road, Pudong New District, Shanghai, 200127, China.
  • Huang C; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, 201210, China.
  • Sun Y; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Hu R; College of Medical Imaging and Shanghai Key Laboratory of Molecular Imaging, Shanghai University of Medicine and Health Sciences, Shanghai, 201318, China.
  • Wang H; Department of Anesthesiology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Center for Specialty Strategy Research of Shanghai Jiao Tong University China Hospital Development Institute, Shanghai, 200011, China.
  • Fu C; Department of Anesthesiology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Center for Specialty Strategy Research of Shanghai Jiao Tong University China Hospital Development Institute, Shanghai, 200011, China.
  • Chen Y; Department of Anesthesiology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Center for Specialty Strategy Research of Shanghai Jiao Tong University China Hospital Development Institute, Shanghai, 200011, China.
  • Jiang H; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, 201210, China.
Sci Rep ; 10(1): 5265, 2020 03 24.
Article in En | MEDLINE | ID: mdl-32210319
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Full text: 1 Database: MEDLINE Main subject: Fentanyl / Flumazenil / Receptors, N-Methyl-D-Aspartate / Dexmedetomidine / GABA-A Receptor Antagonists / Analgesia / Anesthesia / Ketamine / Naltrexone / Narcotic Antagonists Language: En Journal: Sci Rep Year: 2020 Type: Article Affiliation country: China
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Full text: 1 Database: MEDLINE Main subject: Fentanyl / Flumazenil / Receptors, N-Methyl-D-Aspartate / Dexmedetomidine / GABA-A Receptor Antagonists / Analgesia / Anesthesia / Ketamine / Naltrexone / Narcotic Antagonists Language: En Journal: Sci Rep Year: 2020 Type: Article Affiliation country: China