Ameliorative effect of Aloe gel against L-T<sub>4</sub>-induced hyperthyroidism via suppression of thyrotropin receptors, inflammation and oxidative stress.

Panda, Sunanda; Sharma, Rajesh; Khan, Aarif; Kar, Anand

Ameliorative effect of Aloe gel against L-T₄-induced hyperthyroidism via suppression of thyrotropin receptors, inflammation and oxidative stress.

Panda, Sunanda; Sharma, Rajesh; Khan, Aarif; Kar, Anand.

Affiliation

Panda S; School of Pharmacy, Devi Ahilya University, Indore, 452017, India. spanda4@rediffmail.com.
Sharma R; School of Pharmacy, Devi Ahilya University, Indore, 452017, India.
Khan A; School of Life Sciences, Devi Ahilya University, Indore, 452017, India.
Kar A; School of Life Sciences, Devi Ahilya University, Indore, 452017, India.

Mol Biol Rep ; 47(4): 2801-2810, 2020 Apr.

Article in En | MEDLINE | ID: mdl-32242301

Subject(s)

Aloe/metabolism; Hyperthyroidism/drug therapy; Receptors, Thyrotropin/drug effects; Animals; Chromatography, Liquid/methods; Female; Inflammation/drug therapy; Inflammation/metabolism; Liver/metabolism; Oxidative Stress/drug effects; Plant Extracts/pharmacology; Propylthiouracil/pharmacology; Rats; Rats, Wistar; Receptors, Thyrotropin/metabolism; Tandem Mass Spectrometry/methods; Thyroid Gland/drug effects; Thyroid Gland/metabolism; Thyroid Hormones/metabolism; Thyrotropin/blood; Thyrotropin/pharmacology; Thyroxine/adverse effects

Key words

5'D1; Aloe gel; Antioxidants; Cytokines; Hyperthyroidism; TSHR

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Full text: 1 Database: MEDLINE Main subject: Receptors, Thyrotropin / Aloe / Hyperthyroidism Language: En Journal: Mol Biol Rep Year: 2020 Type: Article Affiliation country: India

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