Curcumin micelles suppress gastric tumor cell growth by upregulating ROS generation, disrupting redox equilibrium and affecting mitochondrial bioenergetics.

Lin, Xiaokun; Wang, Lihua; Zhao, Liqian; Zhu, Zheng; Chen, TongZuan; Chen, Shinuo; Tao, Yecheng; Zeng, Tianni; Zhong, Yaoyao; Sun, Hanxiao; Wang, Zhixiang; Zheng, Weisheng; Zhang, Yuhao; Wu, Wencan; Nan, Kaihui; Chen, Tongke

Lin, Xiaokun; Wang, Lihua; Zhao, Liqian; Zhu, Zheng; Chen, TongZuan; Chen, Shinuo; Tao, Yecheng; Zeng, Tianni; Zhong, Yaoyao; Sun, Hanxiao; Wang, Zhixiang; Zheng, Weisheng; Zhang, Yuhao; Wu, Wencan; Nan, Kaihui; Chen, Tongke.

Affiliation

Lin X; Department of Pediatric Surgery, The Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou 325027, Zhejiang, People's Republic of China. dry136@163.com.

Food Funct ; 11(5): 4146-4159, 2020 May 01.

Article in En | MEDLINE | ID: mdl-32347864

Subject(s)

Curcumin/pharmacology; Micelles; Mitochondria/drug effects; Mitochondria/metabolism; Reactive Oxygen Species/metabolism; Stomach Neoplasms/drug therapy; Animals; Cell Line, Tumor; Cell Proliferation/drug effects; Curcumin/chemistry; Gene Expression Regulation/drug effects; Humans; Mice; Mice, Nude; Neoplasms, Experimental/drug therapy; Oxidation-Reduction; Up-Regulation; Xenograft Model Antitumor Assays

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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_energeticas / Bioenergetica Main subject: Stomach Neoplasms / Reactive Oxygen Species / Curcumin / Micelles / Mitochondria Language: En Journal: Food Funct Year: 2020 Type: Article

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