Planning and Analysis of Axon Degeneration Screening Experiments.

Lovell, Lyndah; Bramley, John; Buchser, William

Lovell, Lyndah; Bramley, John; Buchser, William.

Affiliation

Lovell L; Drug Discovery Program, Johns Hopkins University, Baltimore, MD, USA.
Bramley J; Department of Genetics, Washington University in St. Louis, Greater St. Louis, MO, USA.
Buchser W; Department of Genetics, Washington University in St. Louis, Greater St. Louis, MO, USA. wbuchser@wustl.edu.

Methods Mol Biol ; 2143: 63-82, 2020.

Article in En | MEDLINE | ID: mdl-32524473

Subject(s)

Axons/physiology; High-Throughput Screening Assays/methods; Nerve Degeneration/physiopathology; Animals; Axotomy; CRISPR-Cas Systems; Combinatorial Chemistry Techniques; Computer Simulation; Drug Evaluation, Preclinical/methods; Finches/embryology; High-Throughput Screening Assays/instrumentation; Image Processing, Computer-Assisted; Phenotype; Quality Control; RNA Interference; Retinal Ganglion Cells/cytology; Sensitivity and Specificity; Support Vector Machine

Key words

Analysis; Antitargets; Axon degeneration; Discovery; High-throughput; Hits; Nonhits; Screening; Support vector machine learning; Targets

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Axons / High-Throughput Screening Assays / Nerve Degeneration Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Language: En Journal: Methods Mol Biol Year: 2020 Type: Article Affiliation country: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google