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Antitubercular polyhalogenated phenothiazines and phenoselenazine with reduced binding to CNS receptors.
Nizi, Maria Giulia; Desantis, Jenny; Nakatani, Yoshio; Massari, Serena; Mazzarella, Maria Angela; Shetye, Gauri; Sabatini, Stefano; Barreca, Maria Letizia; Manfroni, Giuseppe; Felicetti, Tommaso; Rushton-Green, Rowena; Hards, Kiel; Latacz, Gniewomir; Satala, Grzegorz; Bojarski, Andrzej J; Cecchetti, Violetta; Kolár, Michal H; Handzlik, Jadwiga; Cook, Gregory M; Franzblau, Scott G; Tabarrini, Oriana.
Affiliation
  • Nizi MG; Department of Pharmaceutical Sciences, University of Perugia, Via Del Liceo 1, Perugia, 06100, Italy.
  • Desantis J; Department of Pharmaceutical Sciences, University of Perugia, Via Del Liceo 1, Perugia, 06100, Italy.
  • Nakatani Y; Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.
  • Massari S; Department of Pharmaceutical Sciences, University of Perugia, Via Del Liceo 1, Perugia, 06100, Italy.
  • Mazzarella MA; Department of Pharmaceutical Sciences, University of Perugia, Via Del Liceo 1, Perugia, 06100, Italy.
  • Shetye G; Institute for Tuberculosis Research, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA.
  • Sabatini S; Department of Pharmaceutical Sciences, University of Perugia, Via Del Liceo 1, Perugia, 06100, Italy.
  • Barreca ML; Department of Pharmaceutical Sciences, University of Perugia, Via Del Liceo 1, Perugia, 06100, Italy.
  • Manfroni G; Department of Pharmaceutical Sciences, University of Perugia, Via Del Liceo 1, Perugia, 06100, Italy.
  • Felicetti T; Department of Pharmaceutical Sciences, University of Perugia, Via Del Liceo 1, Perugia, 06100, Italy.
  • Rushton-Green R; Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.
  • Hards K; Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.
  • Latacz G; Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688, Kraków, Poland.
  • Satala G; Department of Medicinal Chemistry May Institute of Pharmacology, Polish Academy of Sciences, Smetna 12, 31-343, Kraków, Poland.
  • Bojarski AJ; Department of Medicinal Chemistry May Institute of Pharmacology, Polish Academy of Sciences, Smetna 12, 31-343, Kraków, Poland.
  • Cecchetti V; Department of Pharmaceutical Sciences, University of Perugia, Via Del Liceo 1, Perugia, 06100, Italy.
  • Kolár MH; Department of Physical Chemistry, University of Chemistry and Technology, Technicka 5, 16628, Prague, Czech Republic.
  • Handzlik J; Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688, Kraków, Poland.
  • Cook GM; Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.
  • Franzblau SG; Institute for Tuberculosis Research, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA.
  • Tabarrini O; Department of Pharmaceutical Sciences, University of Perugia, Via Del Liceo 1, Perugia, 06100, Italy. Electronic address: oriana.tabarrini@unipg.it.
Eur J Med Chem ; 201: 112420, 2020 Sep 01.
Article in En | MEDLINE | ID: mdl-32526553
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Full text: 1 Database: MEDLINE Main subject: Phenothiazines / Organoselenium Compounds / Antitubercular Agents Language: En Journal: Eur J Med Chem Year: 2020 Type: Article Affiliation country: Italy
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Full text: 1 Database: MEDLINE Main subject: Phenothiazines / Organoselenium Compounds / Antitubercular Agents Language: En Journal: Eur J Med Chem Year: 2020 Type: Article Affiliation country: Italy