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pH-dependent ileocolonic drug delivery, part II: preclinical evaluation of novel drugs and novel excipients.
Broesder, Annemarie; Kosta, Anne-Marijke M A C; Woerdenbag, Herman J; Nguyen, Duong N; Frijlink, Henderik W; Hinrichs, Wouter L J.
Affiliation
  • Broesder A; University of Groningen, Groningen Research Institute of Pharmacy, Department of Pharmaceutical Technology and Biopharmacy, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands.
  • Kosta AMAC; University of Groningen, University Medical Center Groningen, Department of Biomedical Sciences of Cells and Systems, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands.
  • Woerdenbag HJ; University of Groningen, Groningen Research Institute of Pharmacy, Department of Pharmaceutical Technology and Biopharmacy, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands.
  • Nguyen DN; University of Groningen, Groningen Research Institute of Pharmacy, Department of Pharmaceutical Technology and Biopharmacy, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands.
  • Frijlink HW; University of Groningen, Groningen Research Institute of Pharmacy, Department of Pharmaceutical Technology and Biopharmacy, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands.
  • Hinrichs WLJ; University of Groningen, Groningen Research Institute of Pharmacy, Department of Pharmaceutical Technology and Biopharmacy, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands. Electronic address: w.l.j.hinrichs@rug.nl.
Drug Discov Today ; 25(8): 1374-1388, 2020 08.
Article in En | MEDLINE | ID: mdl-32562842
Novel drugs and novel excipients in pH-dependent ileocolonic drug delivery systems have to be tested in animals. Which animal species are suitable and what in vivo methods are used to verify ileocolonic drug delivery?
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Full text: 1 Database: MEDLINE Main subject: Pharmaceutical Preparations / Drug Delivery Systems / Colon / Drug Evaluation, Preclinical / Excipients / Ileum Language: En Journal: Drug Discov Today Year: 2020 Type: Article Affiliation country: Netherlands
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Full text: 1 Database: MEDLINE Main subject: Pharmaceutical Preparations / Drug Delivery Systems / Colon / Drug Evaluation, Preclinical / Excipients / Ileum Language: En Journal: Drug Discov Today Year: 2020 Type: Article Affiliation country: Netherlands