Performance tuning of particle engineered mannitol in dry powder inhalation formulations.

Hertel, Nancy; Birk, Gudrun; Scherließ, Regina

Hertel, Nancy; Birk, Gudrun; Scherließ, Regina.

Affiliation

Hertel N; Department of Pharmaceutics and Biopharmaceutics, Kiel University, Grasweg 9a, 24118 Kiel, Germany.
Birk G; Merck KGaA, Frankfurter Straße 250, 64293 Darmstadt, Germany.
Scherließ R; Department of Pharmaceutics and Biopharmaceutics, Kiel University, Grasweg 9a, 24118 Kiel, Germany. Electronic address: rscherliess@pharmazie.uni-kiel.de.

Int J Pharm ; 586: 119592, 2020 Aug 30.

Article in En | MEDLINE | ID: mdl-32622814

Subject(s)

Dry Powder Inhalers; Mannitol; Administration, Inhalation; Drug Carriers; Lactose; Particle Size; Powders

Key words

Aerodynamic performance; Budesonide (PubChem CID: 5281004); Fines; High dose; Magnesium stearate; Magnesium stearate (PubChem CID: 11177); Mannitol (PubChem CID: 6251); Optimisation; Salbutamol sulphate (PubChem CID: 39859)

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Full text: 1 Database: MEDLINE Main subject: Dry Powder Inhalers / Mannitol Language: En Journal: Int J Pharm Year: 2020 Type: Article Affiliation country: Germany

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Full text: 1 Database: MEDLINE Main subject: Dry Powder Inhalers / Mannitol Language: En Journal: Int J Pharm Year: 2020 Type: Article Affiliation country: Germany