In-vitro and in-vivo anti-breast cancer activity of synergistic effect of berberine and exercise through promoting the apoptosis and immunomodulatory effects.

Ma, Wenyu; Zhang, Yaru; Yu, Min; Wang, Bin; Xu, Shiyu; Zhang, Jian; Li, Xuegang; Ye, Xiaoli

Ma, Wenyu; Zhang, Yaru; Yu, Min; Wang, Bin; Xu, Shiyu; Zhang, Jian; Li, Xuegang; Ye, Xiaoli.

Affiliation

Ma W; Chongqing Key Laboratory of Plant Resource Conservation and Germplasm Innovation, School of Life Sciences, Southwest University, Chongqing 400715, China.
Zhang Y; Chongqing Key Laboratory of Plant Resource Conservation and Germplasm Innovation, School of Life Sciences, Southwest University, Chongqing 400715, China.
Yu M; Chongqing Key Laboratory of Plant Resource Conservation and Germplasm Innovation, School of Life Sciences, Southwest University, Chongqing 400715, China.
Wang B; Chongqing Key Laboratory of Plant Resource Conservation and Germplasm Innovation, School of Life Sciences, Southwest University, Chongqing 400715, China.
Xu S; Chongqing Key Laboratory of Plant Resource Conservation and Germplasm Innovation, School of Life Sciences, Southwest University, Chongqing 400715, China.
Zhang J; Chongqing Key Laboratory of Plant Resource Conservation and Germplasm Innovation, School of Life Sciences, Southwest University, Chongqing 400715, China.
Li X; School of Pharmaceutical Sciences, Southwest University, Chongqing 400716, China. Electronic address: Xuegangli@swu.edu.cn.
Ye X; Chongqing Key Laboratory of Plant Resource Conservation and Germplasm Innovation, School of Life Sciences, Southwest University, Chongqing 400715, China. Electronic address: yexiaoli@swu.edu.cn.

Int Immunopharmacol ; 87: 106787, 2020 Oct.

Article in En | MEDLINE | ID: mdl-32707493

Subject(s)

Antineoplastic Agents/therapeutic use; Berberine/therapeutic use; Breast Neoplasms/therapy; Physical Conditioning, Animal; Running; Animals; Antineoplastic Agents/pharmacology; Apoptosis/drug effects; Berberine/pharmacology; Breast Neoplasms/genetics; Breast Neoplasms/metabolism; Cell Line, Tumor; Cell Survival/drug effects; Combined Modality Therapy; Cytokines/genetics; Cytokines/metabolism; Fatty Acids, Volatile/metabolism; Female; Immunomodulation; Mice, Inbred BALB C

Key words

Apoptosis; Berberine (BBR); Combination; Exercise; Immune; SCFAs

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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Plantas_medicinales Main subject: Physical Conditioning, Animal / Running / Berberine / Breast Neoplasms / Antineoplastic Agents Language: En Journal: Int Immunopharmacol Year: 2020 Type: Article Affiliation country: China

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