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Pre-clinical studies of EC2629, a highly potent folate- receptor-targeted DNA crosslinking agent.
Reddy, Joseph A; Nelson, Melissa; Dircksen, Christina; Vetzel, Marilynn; Johnson, Theresa; Cross, Vicky; Westrick, Elaine; Qi, LongWu; Hahn, Spencer; Santhapuram, Hari Krishna; Parham, Garth; Wang, Kevin; Vaughn, Jeremy F; Felten, Albert; Pugh, Michael; Lu, June; Klein, Patrick; Vlahov, Iontcho R; Leamon, Christopher P.
Affiliation
  • Reddy JA; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
  • Nelson M; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
  • Dircksen C; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
  • Vetzel M; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
  • Johnson T; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
  • Cross V; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
  • Westrick E; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
  • Qi L; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
  • Hahn S; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
  • Santhapuram HK; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
  • Parham G; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
  • Wang K; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
  • Vaughn JF; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
  • Felten A; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
  • Pugh M; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
  • Lu J; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
  • Klein P; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
  • Vlahov IR; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
  • Leamon CP; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA. Christopher.Leamon@novartis.com.
Sci Rep ; 10(1): 12772, 2020 07 29.
Article in En | MEDLINE | ID: mdl-32728172

Full text: 1 Database: MEDLINE Main subject: Ovarian Neoplasms / DNA / Endometrial Neoplasms / Cross-Linking Reagents / Folate Receptors, GPI-Anchored / Triple Negative Breast Neoplasms / Antineoplastic Agents Language: En Journal: Sci Rep Year: 2020 Type: Article Affiliation country: United States

Full text: 1 Database: MEDLINE Main subject: Ovarian Neoplasms / DNA / Endometrial Neoplasms / Cross-Linking Reagents / Folate Receptors, GPI-Anchored / Triple Negative Breast Neoplasms / Antineoplastic Agents Language: En Journal: Sci Rep Year: 2020 Type: Article Affiliation country: United States