Role of nutraceutical starch and proanthocyanidins of pigmented rice in regulating hyperglycemia: Enzyme inhibition, enhanced glucose uptake and hepatic glucose homeostasis using in vitro model.

Krishnan, Veda; Rani, Raja; Awana, Monika; Pitale, Durgesh; Kulshreshta, Ankur; Sharma, Susheel; Bollinedi, Haritha; Singh, Archana; Singh, Bhupinder; Singh, A K; Praveen, Shelly

Krishnan, Veda; Rani, Raja; Awana, Monika; Pitale, Durgesh; Kulshreshta, Ankur; Sharma, Susheel; Bollinedi, Haritha; Singh, Archana; Singh, Bhupinder; Singh, A K; Praveen, Shelly.

Affiliation

Krishnan V; Division of Biochemistry, ICAR-Indian Agricultural Research Institute (IARI), New Delhi, India.
Rani R; Division of Biochemistry, ICAR-Indian Agricultural Research Institute (IARI), New Delhi, India.
Awana M; Division of Biochemistry, ICAR-Indian Agricultural Research Institute (IARI), New Delhi, India.
Pitale D; Cell Death and Differentiation Research Laboratory, National Institute of Immunology (NII), New Delhi, India.
Kulshreshta A; CSIR- Institute of Genomics and Integrative Biology, New Delhi, India.
Sharma S; ICAR - Research Complex for NEH Region, Manipur Centre, Lamphelpat, Imphal, India.
Bollinedi H; Division of Genetics, ICAR- Indian Agricultural Research Institute (IARI), New Delhi, India.
Singh A; Division of Biochemistry, ICAR-Indian Agricultural Research Institute (IARI), New Delhi, India.
Singh B; CESCRA-Nuclear Research Laboratory (NRL), ICAR-Indian Agricultural Research Institute (IARI), New Delhi, India.
Singh AK; Division of Genetics, ICAR- Indian Agricultural Research Institute (IARI), New Delhi, India.
Praveen S; Division of Biochemistry, ICAR-Indian Agricultural Research Institute (IARI), New Delhi, India. Electronic address: shelly.parveen@icar.gov.in.

Food Chem ; 335: 127505, 2021 Jan 15.

Article in En | MEDLINE | ID: mdl-32739823

Subject(s)

Glucose/metabolism; Homeostasis; Hyperglycemia/metabolism; Liver/metabolism; Oryza/chemistry; Proanthocyanidins/analysis; Starch/analysis; Biological Transport/drug effects; Dietary Supplements/analysis; Glycoside Hydrolase Inhibitors/pharmacology; Homeostasis/drug effects; Liver/drug effects; Phenol/analysis; Phenol/pharmacology; alpha-Amylases/antagonists & inhibitors

Key words

4-Nitrophenyl α-D glucopyranoside (PubChem CID92969); Acarbose (PubChem CID41774); Anti-hyperglycemic; Black rice; C(14)glucose (PubChem CID6451569); Dinitrosalicyclic acid (PubChem CID11873); Folin's reagent (PubChem CID10636); Gallic acid (PubChem CID370); Gentamycin (PubChem CID3467); Glucose homeostasis; Glucose uptake; Hepatocyte; Penicillin (PubChem CID5904); Pigmented rice; Proanthocyanidins; Propidium iodide (PubChem CID104981); Red rice; Rutin (PubChem CID45479757); Serum albumin (PubChem CID16132389); Starch soluble (PubChem CID 134690613); Streptomycin (PubChem CID19649)

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Full text: 1 Database: MEDLINE Main subject: Oryza / Starch / Proanthocyanidins / Glucose / Homeostasis / Hyperglycemia / Liver Language: En Journal: Food Chem Year: 2021 Type: Article Affiliation country: India

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