Isolation, structural elucidation, and immunoregulation properties of an arabinofuranan from the rinds of Garcinia mangostana.

Zhang, Shaojie; Li, Zhengguo; Wang, Xuelian; An, Lijun; Bao, Jiahe; Zhang, Jie; Cui, Jianlin; Li, Yuhao; Jin, Da-Qing; Tuerhong, Muhetaer; Abudukeremu, Munira; Ohizumi, Yasushi; Xu, Jing; Guo, Yuanqiang

Zhang, Shaojie; Li, Zhengguo; Wang, Xuelian; An, Lijun; Bao, Jiahe; Zhang, Jie; Cui, Jianlin; Li, Yuhao; Jin, Da-Qing; Tuerhong, Muhetaer; Abudukeremu, Munira; Ohizumi, Yasushi; Xu, Jing; Guo, Yuanqiang.

Affiliation

Zhang S; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin 300350, People's Republic of China.
Li Z; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin 300350, People's Republic of China.
Wang X; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin 300350, People's Republic of China.
An L; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin 300350, People's Republic of China.
Bao J; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin 300350, People's Republic of China.
Zhang J; Key Laboratory for Green Processing of Chemical Engineering of Xinjiang Bingtuan, School of Chemistry and Chemical Engineering, Shihezi University, Shihezi 832003, People's Republic of China.
Cui J; School of Medicine, Nankai University, Tianjin 300071, People's Republic of China.
Li Y; School of Medicine, Nankai University, Tianjin 300071, People's Republic of China.
Jin DQ; School of Medicine, Nankai University, Tianjin 300071, People's Republic of China.
Tuerhong M; College of Chemistry and Environmental Sciences, Laboratory of Xinjiang Native Medicinal and Edible Plant Resources Chemistry, Kashgar University, Kashgar 844000, People's Republic of China.
Abudukeremu M; College of Chemistry and Environmental Sciences, Laboratory of Xinjiang Native Medicinal and Edible Plant Resources Chemistry, Kashgar University, Kashgar 844000, People's Republic of China.
Ohizumi Y; Kansei Fukushi Research Institute, Tohoku Fukushi University, Sendai 989-3201, Japan.
Xu J; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin 300350, People's Republic of China; State Key Laboratory of Bioactive Substance and Function of Nat
Guo Y; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin 300350, People's Republic of China. Electronic address: victgyq@nankai.edu.cn.

Carbohydr Polym ; 246: 116567, 2020 Oct 15.

Article in En | MEDLINE | ID: mdl-32747240

Subject(s)

Garcinia mangostana/chemistry; Immunologic Factors/chemistry; Immunologic Factors/pharmacology; Plant Extracts/chemistry; Plant Extracts/pharmacology; Polysaccharides/chemistry; Polysaccharides/pharmacology; Signal Transduction/drug effects; Animals; Cell Survival/drug effects; Cytokines/metabolism; Immunologic Factors/isolation & purification; Macrophages/drug effects; Macrophages/metabolism; Mice; Molecular Weight; Monosaccharides; Nitric Oxide/metabolism; Plant Extracts/isolation & purification; Polysaccharides/isolation & purification; RAW 264.7 Cells; Reactive Oxygen Species/metabolism; Zebrafish/metabolism

Key words

2', 7'-dichlorofluorescein diacetate (PubChem CID: 104913); 3-amino, 4-aminomethyl-2', 7'-difluorescein diacetate (PubChem CID: 2762646); Conformational analysis; Dimethyl sulfoxide (PubChem CID: 679); GCMS; Garcinia mangostana L.; Immunoregulation; Macrophages; Methyl iodide (PubChem CID: 6328); NMR; Penicillin (PubChem CID: 2349); Polysaccharide; Sodium borohydride (PubChem CID: 4311764); Sodium chloride (PubChem CID: 5234); Streptomycin (PubChem CID: 19649); Tricaine (PubChem CID: 261501); Trifluoroacetic acid (PubChem CID: 6422); Zebrafish embryo

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Full text: 1 Database: MEDLINE Main subject: Polysaccharides / Plant Extracts / Signal Transduction / Garcinia mangostana / Immunologic Factors Language: En Journal: Carbohydr Polym Year: 2020 Type: Article

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