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Novel Meroterpenoids from Hypericum patulum: Highly Potent Late Nav1.5 Sodium Current Inhibitors.
Ye, Yan-Song; Du, Shu-Zong; Jiang, Na-Na; Xu, Hong-Xi; Yang, Jian; Fu, Wen-Wei; Nian, Yin; Xu, Gang.
Affiliation
  • Ye YS; State Key Laboratory of Phytochemistry and Plant Resources in West China and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China.
  • Du SZ; University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China.
  • Jiang NN; Key Laboratory of Animal Models and Human Disease Mechanisms and Ion Channel Research and Drug Development Center, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, People's Republic of China.
  • Xu HX; University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China.
  • Yang J; State Key Laboratory of Phytochemistry and Plant Resources in West China and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China.
  • Fu WW; University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China.
  • Nian Y; School of Pharmacy, Shanghai University of Traditional Chinese Medicine and Engineering Research Centre of Shanghai Colleges for TCM New Drug Discovery, Shanghai 201203, People's Republic of China.
  • Xu G; Key Laboratory of Animal Models and Human Disease Mechanisms and Ion Channel Research and Drug Development Center, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, People's Republic of China.
Org Lett ; 22(16): 6339-6343, 2020 08 21.
Article in En | MEDLINE | ID: mdl-32806193
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Full text: 1 Database: MEDLINE Main subject: Sodium / Hypericum / Myocytes, Cardiac Language: En Journal: Org Lett Year: 2020 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Sodium / Hypericum / Myocytes, Cardiac Language: En Journal: Org Lett Year: 2020 Type: Article