Your browser doesn't support javascript.
loading
Phase III study of nivolumab alone or combined with ipilimumab as immunotherapy versus standard of care in resectable head and neck squamous cell carcinoma.
Zech, Henrike B; Moeckelmann, Nikolaus; Boettcher, Arne; Muenscher, Adrian; Binder, Mascha; Vettorazzi, Eik; Bokemeyer, Carsten; Schafhausen, Philippe; Betz, Christian S; Busch, Chia-Jung.
Affiliation
  • Zech HB; Department of Otorhinolaryngology & Head & Neck Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Moeckelmann N; Department of Otorhinolaryngology & Head & Neck Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Boettcher A; Department of Otorhinolaryngology & Head & Neck Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Muenscher A; Department of Otorhinolaryngology & Head & Neck Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Binder M; Department of Internal Medicine IV, University Medical Center Halle (Saale), Germany.
  • Vettorazzi E; Department of Medical Biometry & Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Bokemeyer C; Department of Medical Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Schafhausen P; Department of Medical Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Betz CS; Department of Otorhinolaryngology & Head & Neck Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Busch CJ; Department of Otorhinolaryngology & Head & Neck Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Future Oncol ; 16(36): 3035-3043, 2020 Dec.
Article in En | MEDLINE | ID: mdl-32902312
Subject(s)
Antineoplastic Combined Chemotherapy Protocols/administration & dosage; Head and Neck Neoplasms/therapy; Immune Checkpoint Inhibitors/administration & dosage; Neoadjuvant Therapy/methods; Neoplasm Recurrence, Local/epidemiology; Squamous Cell Carcinoma of Head and Neck/therapy; Adult; Antineoplastic Combined Chemotherapy Protocols/adverse effects; CTLA-4 Antigen/antagonists & inhibitors; CTLA-4 Antigen/metabolism; Chemoradiotherapy, Adjuvant/adverse effects; Chemoradiotherapy, Adjuvant/methods; Chemotherapy, Adjuvant/adverse effects; Chemotherapy, Adjuvant/methods; Cisplatin/administration & dosage; Cisplatin/adverse effects; Disease-Free Survival; Female; Fluorouracil/administration & dosage; Fluorouracil/adverse effects; Head and Neck Neoplasms/diagnosis; Head and Neck Neoplasms/immunology; Head and Neck Neoplasms/mortality; Humans; Immune Checkpoint Inhibitors/adverse effects; Ipilimumab/administration & dosage; Ipilimumab/adverse effects; Male; Middle Aged; Mitomycin/administration & dosage; Mitomycin/adverse effects; Neoadjuvant Therapy/adverse effects; Neoplasm Recurrence, Local/immunology; Neoplasm Recurrence, Local/prevention & control; Neoplasm Staging; Nivolumab/administration & dosage; Nivolumab/adverse effects; Programmed Cell Death 1 Receptor/antagonists & inhibitors; Programmed Cell Death 1 Receptor/metabolism; Prospective Studies; Squamous Cell Carcinoma of Head and Neck/diagnosis; Squamous Cell Carcinoma of Head and Neck/immunology; Squamous Cell Carcinoma of Head and Neck/mortality
Key words
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Database: MEDLINE Main subject: Antineoplastic Combined Chemotherapy Protocols / Neoadjuvant Therapy / Squamous Cell Carcinoma of Head and Neck / Immune Checkpoint Inhibitors / Head and Neck Neoplasms / Neoplasm Recurrence, Local Type of study: Clinical_trials / Diagnostic_studies / Observational_studies / Risk_factors_studies Language: En Journal: Future Oncol Year: 2020 Type: Article Affiliation country: Germany
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Database: MEDLINE Main subject: Antineoplastic Combined Chemotherapy Protocols / Neoadjuvant Therapy / Squamous Cell Carcinoma of Head and Neck / Immune Checkpoint Inhibitors / Head and Neck Neoplasms / Neoplasm Recurrence, Local Type of study: Clinical_trials / Diagnostic_studies / Observational_studies / Risk_factors_studies Language: En Journal: Future Oncol Year: 2020 Type: Article Affiliation country: Germany