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Effects of rhein and Rheum palmatum L. extract on the pharmacokinetics and tissue distribution of aristolochic acid I and its demethylated metabolite in rats.
Ma, Liping; Shen, Zhuowei; Hu, Haihong; Zhou, Hui; Yu, Lushan; Jiang, Huidi; Zeng, Su.
Affiliation
  • Ma L; Laboratory of Pharmaceutical Analysis and Drug Metabolism, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058, China; Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiaoto
  • Shen Z; Laboratory of Pharmaceutical Analysis and Drug Metabolism, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058, China.
  • Hu H; Laboratory of Pharmaceutical Analysis and Drug Metabolism, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058, China.
  • Zhou H; Laboratory of Pharmaceutical Analysis and Drug Metabolism, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058, China.
  • Yu L; Laboratory of Pharmaceutical Analysis and Drug Metabolism, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058, China.
  • Jiang H; Laboratory of Pharmaceutical Analysis and Drug Metabolism, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058, China.
  • Zeng S; Laboratory of Pharmaceutical Analysis and Drug Metabolism, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058, China. Electronic address: zengsu@zju.edu.cn.
J Ethnopharmacol ; 267: 113537, 2021 Mar 01.
Article in En | MEDLINE | ID: mdl-33137430
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Full text: 1 Database: MEDLINE Main subject: Rheum / Plant Extracts / Anthraquinones / Organic Anion Transporters, Sodium-Independent / Organic Anion Transport Protein 1 / Aristolochic Acids Language: En Journal: J Ethnopharmacol Year: 2021 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Rheum / Plant Extracts / Anthraquinones / Organic Anion Transporters, Sodium-Independent / Organic Anion Transport Protein 1 / Aristolochic Acids Language: En Journal: J Ethnopharmacol Year: 2021 Type: Article