Anti-Vascular Inflammatory Effect of Ethanol Extract from <i>Securinega suffruticosa</i> in Human Umbilical Vein Endothelial Cells.

Han, Byung Hyuk; Song, Chun Ho; Yoon, Jung Joo; Kim, Hye Yoom; Seo, Chang Seob; Kang, Dae Gill; Lee, Yun Jung; Lee, Ho Sub

Anti-Vascular Inflammatory Effect of Ethanol Extract from Securinega suffruticosa in Human Umbilical Vein Endothelial Cells.

Han, Byung Hyuk; Song, Chun Ho; Yoon, Jung Joo; Kim, Hye Yoom; Seo, Chang Seob; Kang, Dae Gill; Lee, Yun Jung; Lee, Ho Sub.

Affiliation

Han BH; Hanbang Cardio-Renal Syndrome Research Center, Wonkwang University, 460, Iksan-daero, Iksan 54538, Jeonbuk, Korea.
Song CH; College of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, 460, Iksan-daero, Iksan 54538, Jeonbuk, Korea.
Yoon JJ; Hanbang Cardio-Renal Syndrome Research Center, Wonkwang University, 460, Iksan-daero, Iksan 54538, Jeonbuk, Korea.
Kim HY; College of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, 460, Iksan-daero, Iksan 54538, Jeonbuk, Korea.
Seo CS; Hanbang Cardio-Renal Syndrome Research Center, Wonkwang University, 460, Iksan-daero, Iksan 54538, Jeonbuk, Korea.
Kang DG; College of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, 460, Iksan-daero, Iksan 54538, Jeonbuk, Korea.
Lee YJ; Hanbang Cardio-Renal Syndrome Research Center, Wonkwang University, 460, Iksan-daero, Iksan 54538, Jeonbuk, Korea.
Lee HS; College of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, 460, Iksan-daero, Iksan 54538, Jeonbuk, Korea.

Nutrients ; 12(11)2020 Nov 10.

Article in En | MEDLINE | ID: mdl-33182831

Subject(s)

Anti-Inflammatory Agents/pharmacology; Human Umbilical Vein Endothelial Cells/drug effects; Inflammation/prevention & control; Plant Extracts/pharmacology; Securinega/chemistry; Ethanol/isolation & purification; Human Umbilical Vein Endothelial Cells/cytology; Human Umbilical Vein Endothelial Cells/metabolism; Humans; Inflammation/metabolism; Intercellular Adhesion Molecule-1/genetics; Intercellular Adhesion Molecule-1/metabolism; Lipoproteins, LDL; NF-kappa B/metabolism; Nitric Oxide Synthase Type III/metabolism; Plant Extracts/chemistry; Proto-Oncogene Proteins c-akt/metabolism; Reactive Oxygen Species/metabolism; Tumor Necrosis Factor-alpha/metabolism; Vascular Cell Adhesion Molecule-1/genetics; Vascular Cell Adhesion Molecule-1/metabolism

Key words

HUVECs; NO; Securiniga suffruticosa; TNF-α; adhesion molecules; vascular inflammation

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Full text: 1 Database: MEDLINE Main subject: Plant Extracts / Human Umbilical Vein Endothelial Cells / Securinega / Inflammation / Anti-Inflammatory Agents Language: En Journal: Nutrients Year: 2020 Type: Article

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