Combined treatment of sorafenib and doxorubicin-loaded microbubble-albumin nanoparticle complex for hepatocellular carcinoma: A feasibility study.

Lee, Seunghyun; Kim, Jung Hoon; Moon, Hyungwon; Lee, Hak Jong; Han, Joon Koo

Lee, Seunghyun; Kim, Jung Hoon; Moon, Hyungwon; Lee, Hak Jong; Han, Joon Koo.

Affiliation

Lee S; Department of Radiology, Seoul National University Hospital, Jongno-gu, Seoul, Republic of Korea.
Kim JH; Department of Radiology, Seoul National University Hospital, Jongno-gu, Seoul, Republic of Korea.
Moon H; Department of Radiology, Seoul National University College of Medicine, Jongno-gu, Seoul, Republic of Korea.
Lee HJ; Institute of Radiation Medicine, Seoul National University Medical Research Center, Jongno-gu, Seoul, Republic of Korea.
Han JK; IMGT Co., Ltd., Bundang-gu, Seongnam, Republic of Korea.

PLoS One ; 15(12): e0243815, 2020.

Article in En | MEDLINE | ID: mdl-33306731

Subject(s)

Albumins/chemistry; Carcinoma, Hepatocellular/pathology; Doxorubicin/pharmacology; Liver Neoplasms/pathology; Microbubbles; Nanoparticles/chemistry; Sorafenib/pharmacology; Animals; Body Weight/drug effects; Cell Line, Tumor; Doxorubicin/chemistry; Drug Carriers/chemistry; Drug Interactions; Feasibility Studies; Humans; Rats; Sorafenib/chemistry; Tumor Burden/drug effects; Xenograft Model Antitumor Assays

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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_biologicas / Aromoterapia Main subject: Doxorubicin / Carcinoma, Hepatocellular / Microbubbles / Albumins / Nanoparticles / Sorafenib / Liver Neoplasms Type of study: Prognostic_studies Language: En Journal: PLoS One Year: 2020 Type: Article

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