Rutin present in Alibertia edulis extract acts on human platelet aggregation through inhibition of cyclooxygenase/thromboxane.

Lescano, Caroline Honaiser; Freitas de Lima, Fernando; Cardoso, Claudia Andrea Lima; Vieira, Silvia Cristina Heredia; Mónica, Fabíola Zakia; Pires de Oliveira, Ivan

Lescano, Caroline Honaiser; Freitas de Lima, Fernando; Cardoso, Claudia Andrea Lima; Vieira, Silvia Cristina Heredia; Mónica, Fabíola Zakia; Pires de Oliveira, Ivan.

Affiliation

Lescano CH; Department of Pharmacology, Faculty of Medical Sciences, University of Campinas, Campinas, Brazil. carolinehonaiser@gmail.com lescano@unicamp.br.

Food Funct ; 12(2): 802-814, 2021 Jan 21.

Article in En | MEDLINE | ID: mdl-33393955

Subject(s)

Gene Expression Regulation/drug effects; Plant Extracts/pharmacology; Platelet Aggregation/drug effects; Prostaglandin-Endoperoxide Synthases/metabolism; Rubiaceae/chemistry; Thromboxanes/antagonists & inhibitors; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid/administration & dosage; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid/pharmacology; Adenosine Diphosphate/administration & dosage; Adenosine Diphosphate/pharmacology; Animals; Arachidonic Acid/administration & dosage; Arachidonic Acid/pharmacology; Calcium/metabolism; Collagen/administration & dosage; Collagen/pharmacology; Cyclooxygenase Inhibitors; Humans; Plant Extracts/chemistry; Plant Leaves/chemistry; Thromboxanes/genetics; Thromboxanes/metabolism; Zebrafish

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Full text: 1 Database: MEDLINE Main subject: Plant Extracts / Platelet Aggregation / Thromboxanes / Gene Expression Regulation / Prostaglandin-Endoperoxide Synthases / Rubiaceae Language: En Journal: Food Funct Year: 2021 Type: Article

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