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Loss of NRF2 accelerates cognitive decline, exacerbates mitochondrial dysfunction, and is required for the cognitive enhancing effects of Centella asiatica during aging.
Zweig, Jonathan A; Brandes, Mikah S; Brumbach, Barbara H; Caruso, Maya; Wright, Kirsten M; Quinn, Joseph F; Soumyanath, Amala; Gray, Nora E.
Affiliation
  • Zweig JA; Department of Neurology, Oregon Health & Science University, Portland, OR, USA.
  • Brandes MS; Department of Neurology, Oregon Health & Science University, Portland, OR, USA.
  • Brumbach BH; Biostatistics & Design Program, Oregon Health & Science University, Portland, OR, USA.
  • Caruso M; Department of Neurology, Oregon Health & Science University, Portland, OR, USA.
  • Wright KM; Department of Neurology, Oregon Health & Science University, Portland, OR, USA.
  • Quinn JF; Department of Neurology, Oregon Health & Science University, Portland, OR, USA; Department of Neurology and Parkinson's Disease Research Education and Clinical Care Center (PADRECC), VA Portland Healthcare System, Portland, OR, USA.
  • Soumyanath A; Department of Neurology, Oregon Health & Science University, Portland, OR, USA.
  • Gray NE; Department of Neurology, Oregon Health & Science University, Portland, OR, USA. Electronic address: grayn@ohsu.edu.
Neurobiol Aging ; 100: 48-58, 2021 04.
Article in En | MEDLINE | ID: mdl-33486357

Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_biologicas / Plantas_medicinales Main subject: Triterpenes / Aging / Cognition / Mitochondrial Diseases / NF-E2-Related Factor 2 / Cognitive Dysfunction / Phytotherapy / Antioxidants Language: En Journal: Neurobiol Aging Year: 2021 Type: Article Affiliation country: United States

Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_biologicas / Plantas_medicinales Main subject: Triterpenes / Aging / Cognition / Mitochondrial Diseases / NF-E2-Related Factor 2 / Cognitive Dysfunction / Phytotherapy / Antioxidants Language: En Journal: Neurobiol Aging Year: 2021 Type: Article Affiliation country: United States