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Gene therapy via canalostomy approach preserves auditory and vestibular functions in a mouse model of Jervell and Lange-Nielsen syndrome type 2.
Wu, Xuewen; Zhang, Li; Li, Yihui; Zhang, Wenjuan; Wang, Jianjun; Cai, Cuiyun; Lin, Xi.
Affiliation
  • Wu X; Department of Otolaryngology Head and Neck Surgery, Xiangya Hospital of Central South University, 87 Xiangya Road, 410008, Changsha, Hunan, China.
  • Zhang L; Department of Otolaryngology, Emory University School of Medicine, 615 Michael Street, Atlanta, GA, 30322, USA.
  • Li Y; Department of Otolaryngology, Emory University School of Medicine, 615 Michael Street, Atlanta, GA, 30322, USA.
  • Zhang W; Department of Otolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Wang J; Department of Pharmacy, Changsha Hospital of Traditional Medicine, 22 Xingsha Avenue, 410100, Changsha, Hunan, China.
  • Cai C; Department of Otolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Lin X; Department of Otolaryngology, Emory University School of Medicine, 615 Michael Street, Atlanta, GA, 30322, USA.
Nat Commun ; 12(1): 697, 2021 01 29.
Article in En | MEDLINE | ID: mdl-33514733
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Full text: 1 Database: MEDLINE Main subject: Genetic Therapy / Semicircular Canals / Jervell-Lange Nielsen Syndrome / Potassium Channels, Voltage-Gated / Genetic Vectors Type of study: Prognostic_studies Language: En Journal: Nat Commun Year: 2021 Type: Article Affiliation country: China
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Full text: 1 Database: MEDLINE Main subject: Genetic Therapy / Semicircular Canals / Jervell-Lange Nielsen Syndrome / Potassium Channels, Voltage-Gated / Genetic Vectors Type of study: Prognostic_studies Language: En Journal: Nat Commun Year: 2021 Type: Article Affiliation country: China