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The benzylisoquinoline alkaloids, berberine and coptisine, act against camptothecin-resistant topoisomerase I mutants.
Inoue, Naomi; Terabayashi, Takeshi; Takiguchi-Kawashima, Yuri; Fujinami, Daisuke; Matsuoka, Shigeru; Kawano, Masanori; Tanaka, Kazuhiro; Tsumura, Hiroshi; Ishizaki, Toshimasa; Narahara, Hisashi; Kohda, Daisuke; Nishida, Yoshihiro; Hanada, Katsuhiro.
Affiliation
  • Inoue N; Department of Obstetrics and Gynecology, Faculty of Medicine, Oita University, 1-1 Idaigaoka, Hasama-machi, Yufu, Oita, 879-5593, Japan.
  • Terabayashi T; Department of Pharmacology, Faculty of Medicine, Oita University, Yufu, Japan.
  • Takiguchi-Kawashima Y; Clinical Engineering Research Center, Faculty of Medicine, Oita University, 1-1 Idaigaoka, Hasama-machi, Yufu, Oita, 879-5593, Japan.
  • Fujinami D; Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Tokyo, Japan.
  • Matsuoka S; Division of Structural Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
  • Kawano M; Department of Clinical Biology Ant Therapeutics, Faculty of Medicine, Oita University, Yufu, Japan.
  • Tanaka K; Department of Orthopaedic Surgery, Faculty of Medicine, Oita University, Yufu, Japan.
  • Tsumura H; Department of Orthopaedic Surgery, Faculty of Medicine, Oita University, Yufu, Japan.
  • Ishizaki T; Department of Orthopaedic Surgery, Faculty of Medicine, Oita University, Yufu, Japan.
  • Narahara H; Department of Pharmacology, Faculty of Medicine, Oita University, Yufu, Japan.
  • Kohda D; Department of Obstetrics and Gynecology, Faculty of Medicine, Oita University, 1-1 Idaigaoka, Hasama-machi, Yufu, Oita, 879-5593, Japan.
  • Nishida Y; Division of Structural Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
  • Hanada K; Department of Obstetrics and Gynecology, Faculty of Medicine, Oita University, 1-1 Idaigaoka, Hasama-machi, Yufu, Oita, 879-5593, Japan. ynishida@oita-u.ac.jp.
Sci Rep ; 11(1): 7718, 2021 04 08.
Article in En | MEDLINE | ID: mdl-33833336
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Full text: 1 Database: MEDLINE Main subject: Berberine / Camptothecin / Drug Resistance, Neoplasm / Topoisomerase I Inhibitors / Antineoplastic Agents, Phytogenic Language: En Journal: Sci Rep Year: 2021 Type: Article Affiliation country: Japan
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Full text: 1 Database: MEDLINE Main subject: Berberine / Camptothecin / Drug Resistance, Neoplasm / Topoisomerase I Inhibitors / Antineoplastic Agents, Phytogenic Language: En Journal: Sci Rep Year: 2021 Type: Article Affiliation country: Japan